Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration (Q33725698)

28 July 2017

title

Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration (English)

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28 July 2017

Nicolas Ruffin

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Liv Eidsmo

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Susanne Nylén

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Hannah Akuffo

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Francesca Chiodi

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Geremew Tasew

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28 July 2017

Thorsten Lieke

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28 July 2017

Dawit Wolday

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28 July 2017

Befekadu Lemu

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28 July 2017

Hailu Meless

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28 July 2017

Abraham Asseffa

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28 July 2017

Hideo Yagita

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28 July 2017

Sven Britton

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28 July 2017

language of work or name

English

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publication date

12 October 2010

1 reference

PLoS Neglected Tropical Diseases

28 July 2017

published in

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

e844

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Creative Commons Attribution 4.0 International

28 July 2017

start time

12 October 2010

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps

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IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice

21 June 2018

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In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies.

21 June 2018

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Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani

21 June 2018

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FasL and TRAIL induce epidermal apoptosis and skin ulceration upon exposure to Leishmania major.

21 June 2018

1 reference

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The contribution of the Fas/FasL apoptotic pathway in ulcer formation during Leishmania major-induced cutaneous Leishmaniasis.

21 June 2018

1 reference

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Both the Fas ligand and inducible nitric oxide synthase are needed for control of parasite replication within lesions in mice infected with Leishmania major whereas the contribution of tumor necrosis factor is minimal

21 June 2018

1 reference

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Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

21 June 2018

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Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva preexposure on the long-term outcome of Leishmania major infection in the mouse ear dermis

21 June 2018

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Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production.

21 June 2018

1 reference

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Polymorphism of murine Fas ligand that affects the biological activity

21 June 2018

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A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice

21 June 2018

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Studies on leishmaniasis in Ethiopia. I. Preliminary investigations into the epidemiology of cutaneous leishmaniasis in the highlands

21 June 2018

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Metacyclogenesis is a major determinant of Leishmania promastigote virulence and attenuation

21 June 2018

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Differential recognition of Leishmania aethiopica antigens by lymphocytes from patients with local and diffuse cutaneous leishmaniasis. Evidence for antigen-induced immune suppression

21 June 2018

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Responsiveness in diffuse versus local cutaneous leishmaniasis is due to parasite differences.

21 June 2018

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Effects of intradermal gamma-interferon in cutaneous leishmaniasis.

21 June 2018

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Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

21 June 2018

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A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity.

21 June 2018

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The potency and durability of DNA- and protein-based vaccines against Leishmania major evaluated using low-dose, intradermal challenge.

21 January 2018

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A new function of the Fas-FasL pathway in macrophage activation

21 January 2018

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The role of polymorphonuclear leukocytes in the resistance to cutaneous Leishmaniasis.

21 January 2018

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Leishmania aethiopica derived from diffuse leishmaniasis patients preferentially induce mRNA for interleukin-10 while those from localized leishmaniasis patients induce interferon-gamma

21 January 2018

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Increased expression of fas ligand in human tuberculosis and leprosy lesions: a potential novel mechanism of immune evasion in mycobacterial infection

30 October 2018

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12 December 2020

Diffuse cutaneous leishmaniasis in Ethiopia. 3. Immunological studies. IV. Pathogenesis of diffuse cutaneous leishmaniasis

1 reference

12 December 2020

Leishmania species: comparative ultrastructure of experimental nodules and diffuse human cutaneous lesions in American leishmaniases

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12 December 2020

Electron microscopical studies on cutaneous leishmaniasis in Ethiopia. II. Parasite and host cell differences between the localized and the diffuse form

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12 December 2020

The resolution of lesions induced byLeishmania major in mice requires a functional Fas (APO-1, CD 95) pathway of cytotoxicity

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12 December 2020

Cellular analysis of cutaneous leishmaniasis lymphadenopathy: insights into the early phases of human disease

1 reference

12 December 2020

10.1371/JOURNAL.PNTD.0000844

Identifiers

DOI

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28 July 2017

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28 July 2017

1 reference