Hybrid lentivirus-transposon vectors with a random integration profile in human cells. (Q33713812)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240688%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Hybrid lentivirus-transposon vectors with a random integration profile in human cells (English)

1 reference

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22 January 2020

author

Nicklas Heine Staunstrup

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22 January 2020

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22 January 2020

Jacob Giehm Mikkelsen

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22 January 2020

Zoltán Ivics

1 reference

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22 January 2020

Zsuzsanna Izsvák

1 reference

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22 January 2020

Brian Moldt

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22 January 2020

Lajos Mátés

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22 January 2020

Maria Jakobsen

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22 January 2020

publication date

24 February 2009

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22 January 2020

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22 January 2020

volume

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22 January 2020

issue

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22 January 2020

page(s)

1205-1214

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Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

22 January 2020

cites work

1 reference

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Genomic insertion of lentiviral DNA circles directed by the yeast Flp recombinase

21 June 2018

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Integration site selection by retroviral vectors: molecular mechanism and clinical consequences

21 June 2018

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

21 June 2018

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Stable gene transfer to muscle using non-integrating lentiviral vectors

21 June 2018

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21 June 2018

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21 June 2018

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Targeted Sleeping Beauty transposition in human cells

21 June 2018

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21 June 2018

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21 June 2018

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An essential role for LEDGF/p75 in HIV integration

21 June 2018

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21 June 2018

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Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

21 June 2018

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Transient gene expression by nonintegrating lentiviral vectors

21 June 2018

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Effective gene therapy with nonintegrating lentiviral vectors

21 June 2018

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Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts.

21 June 2018

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A role for LEDGF/p75 in targeting HIV DNA integration

21 June 2018

1 reference

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Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

21 June 2018

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High-resolution genome-wide mapping of transposon integration in mammals

21 June 2018

1 reference

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Genome-wide analyses of avian sarcoma virus integration sites

21 June 2018

1 reference

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Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells

21 June 2018

1 reference

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Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

21 June 2018

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Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system

21 June 2018

1 reference

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Endothelial targeting of the Sleeping Beauty transposon within lung

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Enhancement of Sleeping Beauty transposition by CpG methylation: possible role of heterochromatin formation

21 June 2018

1 reference

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Sleeping beauty transposition: biology and applications for molecular therapy

21 June 2018

1 reference

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Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites

21 June 2018

1 reference

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Nonhomologous-End-Joining Factors Regulate DNA Repair Fidelity during Sleeping Beauty Element Transposition in Mammalian Cells

21 June 2018

1 reference

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 June 2018

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Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer

21 June 2018

1 reference

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Transcription start regions in the human genome are favored targets for MLV integration

21 June 2018

1 reference

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LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

21 June 2018

1 reference

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HIV-1 integration in the human genome favors active genes and local hotspots

21 June 2018

1 reference

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Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication

21 June 2018

1 reference

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Human immunodeficiency virus cDNA metabolism: notable stability of two-long terminal repeat circles

21 June 2018

1 reference

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A quantitative assay for HIV DNA integration in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Human immunodeficiency virus type 1 integrase mutants retain in vitro integrase activity yet fail to integrate viral DNA efficiently during infection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Human immunodeficiency virus type 1 2-LTR circles reside in a nucleoprotein complex which is different from the preintegration complex.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Splinkerettes--improved vectorettes for greater efficiency in PCR walking.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Targeted genome modifications using integrase-deficient lentiviral vectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

HIV integration site selection: targeting in macrophages and the effects of different routes of viral entry.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Target-site preferences of Sleeping Beauty transposons.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Novel integrase-defective lentiviral episomal vectors for gene transfer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835219

30 October 2018

Identifiers

DOI

10.1038/MT.2009.10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240688%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240688%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

19240688

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19240688%20AND%20SRC:MED&resulttype=core&format=json