Enabling a genetically informed approach to cancer medicine: a retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel (Q33699641)

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English	Enabling a genetically informed approach to cancer medicine: a retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel	scientific article

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scholarly article

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Europe PubMed Central

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28 July 2017

Enabling a genetically informed approach to cancer medicine: a retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel (English)

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28 July 2017

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William Pao

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28 July 2017

Justin M. Balko

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Justin M Balko

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28 July 2017

Christine M. Lovly

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Christine M Lovly

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28 July 2017

Jeffrey A Sosman

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Jeffrey A Sosman

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28 July 2017

Carlos L Arteaga

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Carlos L Arteaga

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28 July 2017

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Douglas B Johnson

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28 July 2017

Kimberly H Dahlman

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28 July 2017

Jared Knol

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28 July 2017

Jill Gilbert

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28 July 2017

Igor Puzanov

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28 July 2017

Julie Means-Powell

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28 July 2017

Barbara A Murphy

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28 July 2017

Laura W Goff

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Vandana G Abramson

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28 July 2017

Marta A Crispens

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28 July 2017

Ingrid A Mayer

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28 July 2017

Jordan D Berlin

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28 July 2017

Leora Horn

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28 July 2017

Vicki L Keedy

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28 July 2017

Nishitha M Reddy

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28 July 2017

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5 May 2014

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

616-622

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28 July 2017

Beyond histology: translating tumor genotypes into clinically effective targeted therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041676

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BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition

1 reference

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Technical and implementation issues in using next-generation sequencing of cancers in clinical practice

1 reference

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Crizotinib versus chemotherapy in advanced ALK-positive lung cancer.

1 reference

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Major clinical response to a BRAF inhibitor in a patient with a BRAF L597R-mutated melanoma

1 reference

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Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma.

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Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas

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MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study

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Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study

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Genome sequencing identifies a basis for everolimus sensitivity

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BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors

1 reference

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High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing

1 reference

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Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

1 reference

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21 June 2018

Analytical performance of a real-time PCR-based assay for V600 mutations in the BRAF gene, used as the companion diagnostic test for the novel BRAF inhibitor vemurafenib in metastatic melanoma

1 reference

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21 June 2018

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study

1 reference

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21 June 2018

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

1 reference

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21 June 2018

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

1 reference

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21 June 2018

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

1 reference

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21 June 2018

The first 30 years of p53: growing ever more complex

1 reference

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21 June 2018

Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

1 reference

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21 June 2018

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

1 reference

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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

1 reference

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21 June 2018

Mutations of the BRAF gene in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041676

21 June 2018

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

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A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumors

1 reference

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ras oncogenes in human cancer: a review

1 reference

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Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

1 reference

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Dramatic response induced by vemurafenib in a BRAF V600E-mutated lung adenocarcinoma

1 reference

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Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

1 reference

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Targeting p53 in vivo: a first-in-human study with p53-targeting compound APR-246 in refractory hematologic malignancies and prostate cancer

1 reference

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12 December 2020

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10.1634/THEONCOLOGIST.2014-0011

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Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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