The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice. (Q33686145)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10403638%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

review article

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title

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10403638%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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10 December 2019

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10 December 2019

K Schulze-Osthoff

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10 December 2019

language of work or name

English

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publication date

1 June 1999

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10 December 2019

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10 December 2019

volume

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issue

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10 December 2019

page(s)

629-639

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Human ICE/CED-3 protease nomenclature

10 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Defects in regulation of apoptosis in caspase-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Molecular cloning of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Activation of the STAT Signaling Pathway Can Cause Expression of Caspase 1 and Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

1 reference

7 January 2021

RAIDD is a new 'death' adaptor molecule

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Mechanisms and Functions of Cell Death

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Apoptosis in cancer therapy: crossing the threshold

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Inhibition of ICE slows ALS in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Inhibition of human caspases by peptide-based and macromolecular inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

CD95(APO-1/Fas)-mediated apoptosis: live and let die

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Identification of a set of genes with developmentally down-regulated expression in the mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Activation of Caspase-2 in Apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Characterization of mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Bcl-XL cooperatively associates with the Bap31 complex in the endoplasmic reticulum, dependent on procaspase-8 and Ced-4 adaptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

E1A-induced processing of procaspase-8 can occur independently of FADD and is inhibited by Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Caspases: killer proteases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Severity and mortality of experimental pancreatitis are dependent on interleukin-1 converting enzyme (ICE)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Apoptosis signaling by death receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

DCP-1, a Drosophila cell death protease essential for development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Death by a thousand cuts: an ever increasing list of caspase substrates

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Possible involvement of caspase-like family in maintenance of cytoskeleton integrity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Structure and mechanism of interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Endothelial apoptosis in Braf-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980062-X

7 January 2021