Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases (Q33677369)

28 July 2017

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title

Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases (English)

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28 July 2017

main subject

cardiovascular disease

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Colin Sumners

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28 July 2017

Anderson J Ferreira

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28 July 2017

Robson A S Santos

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28 July 2017

Chastity N Bradford

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28 July 2017

Adam P Mecca

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28 July 2017

Michael J Katovich

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28 July 2017

Mohan K Raizada

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28 July 2017

language of work or name

English

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publication date

28 December 2009

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

207-213

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Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes.

28 July 2017

cites work

1 reference

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Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer.

28 July 2018

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Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

28 July 2018

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Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease

28 July 2018

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Are we poised to target ACE2 for the next generation of antihypertensives?

28 July 2018

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Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats

28 July 2018

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Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation

28 July 2018

1 reference

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Study of angiotensin-(1-7) vasoactive peptide and its beta-cyclodextrin inclusion complexes: complete sequence-specific NMR assignments and structural studies

28 July 2018

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Renin-angiotensin system and cardiovascular risk

28 July 2018

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Alterations in gene expression in the testis of angiotensin-(1-7)-receptor Mas-deficient mice.

28 July 2018

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Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system

28 July 2018

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Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice.

28 July 2018

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Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis

28 July 2018

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Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular function

28 July 2018

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Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins

28 July 2018

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Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

28 July 2018

1 reference

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Angiotensin-converting enzyme 2 is an essential regulator of heart function

28 July 2018

1 reference

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Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria

28 July 2018

1 reference

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Onset of experimental severe cardiac fibrosis is mediated by overexpression of Angiotensin-converting enzyme 2.

30 October 2018

1 reference

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Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

30 October 2018

1 reference

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Angiotensin-converting enzyme 2 in the brain: properties and future directions

30 October 2018

1 reference

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Central administration of angiotensin-(1-7) stimulates nitric oxide release and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats

30 October 2018

1 reference

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Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.

30 October 2018

1 reference

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Chronic angiotensin (1-7) injection accelerates STZ-induced diabetic renal injury

30 October 2018

1 reference

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Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology

30 October 2018

1 reference

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Endothelial dysfunction through genetic deletion or inhibition of the G protein-coupled receptor Mas: a new target to improve endothelial function

30 October 2018

1 reference

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Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice.

30 October 2018

1 reference

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Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats

30 October 2018

1 reference

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Enalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat

30 October 2018

1 reference

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ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR.

30 October 2018

1 reference

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Developmental expression of ACE2 in the SHR kidney: a role in hypertension?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Short-term angiotensin(1-7) receptor MAS stimulation improves endothelial function in normotensive rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Angiotensin-converting enzyme 2 protects from severe acute lung failure

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Sodium status and angiotensin-converting enzyme inhibition: effects on plasma angiotensin-(1-7) in healthy man.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Update on the role of the AT2 receptor

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Systemic and regional hemodynamic effects of angiotensin-(1-7) in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

AVE 0991, a nonpeptide mimic of the effects of angiotensin-(1-7) on the endothelium

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Angiotensin-(1-7): cardioprotective effect in myocardial ischemia/reperfusion

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Molecular Mechanisms Involved in the Angiotensin-(1-7)/Mas Signaling Pathway in Cardiomyocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

Impairment of In Vitro and In Vivo Heart Function in Angiotensin-(1-7) Receptor Mas Knockout Mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826213

The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE-0991 attenuates heart failure induced by myocardial infarction

30 October 2018

1 reference

12 December 2020

Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7)

1 reference

12 December 2020

Effects of intracerebroventricular infusion of angiotensin-(1-7) on bradykinin formation and the kinin receptor expression after focal cerebral ischemia-reperfusion in rats

1 reference

12 December 2020

Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog

1 reference

12 December 2020

An oral formulation of angiotensin-(1-7) produces cardioprotective effects in infarcted and isoproterenol-treated rats

1 reference

12 December 2020

Effect of angiotensin-(1-7) on reperfusion arrhythmias in isolated rat hearts

1 reference

12 December 2020

Metabolism of Angiotensin-(1–7) by Angiotensin-Converting Enzyme

1 reference

12 December 2020

Vasodepressor Actions of Angiotensin-(1–7) Unmasked During Combined Treatment With Lisinopril and Losartan

1 reference

12 December 2020

Renal ACE2 expression in human kidney disease

1 reference

12 December 2020

10.1161/HYPERTENSIONAHA.109.140145

Identifiers

DOI

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28 July 2017

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28 July 2017

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