The chosen few? Positive selection and the generation of naive B lymphocytes (Q33657947)

28 July 2017

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title

The chosen few? Positive selection and the generation of naive B lymphocytes (English)

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28 July 2017

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Pillai S

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28 July 2017

language of work or name

English

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publication date

1 May 1999

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

493-502

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Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen.

28 July 2017

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Tyrosine phosphorylation of Blk and Fyn Src homology 2 domain-binding proteins occurs in response to antigen-receptor ligation in B cells and constitutively in pre-B cells

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CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells

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7 January 2021

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

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7 January 2021

Transitional B cells are the target of negative selection in the B cell compartment

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7 January 2021

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

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7 January 2021

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus

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7 January 2021

Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone

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7 January 2021

Syk tyrosine kinase required for mouse viability and B-cell development

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7 January 2021

B-1 cell development: evidence for an uncommitted immunoglobulin (Ig)M+ B cell precursor in B-1 cell differentiation

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7 January 2021

Outer Periarteriolar Lymphoid Sheath Arrest and Subsequent Differentiation of Both Naive and Tolerant Immunoglobulin Transgenic B Cells Is Determined by B Cell Receptor Occupancy

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7 January 2021

Oct-2 is required early in T cell-independent B cell activation for G1 progression and for proliferation

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7 January 2021

Pre-B-cell development in the absence of lambda 5 in transgenic mice expressing a heavy-chain disease protein

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7 January 2021

Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection.

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7 January 2021

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

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7 January 2021

Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45

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7 January 2021

Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development

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7 January 2021

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

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7 January 2021

Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene.

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7 January 2021

Requirement for NF-kappaB in osteoclast and B-cell development

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7 January 2021

The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow

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7 January 2021

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

1 reference

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7 January 2021

Influences on the lifespan of B cell subpopulations defined by different phenotypes.

1 reference

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7 January 2021

Transcription factors in lymphocyte development--T and B cells get together

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7 January 2021

Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.

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7 January 2021

Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires

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7 January 2021

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

1 reference

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7 January 2021

Most peripheral B cells in mice are ligand selected

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

A developmental switch in B lymphopoiesis

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

B-1 cells are made, not born

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

BCR ligation induces receptor editing in IgM+IgD- bone marrow B cells in vitro

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7 January 2021

The Ly-1 B cell lineage

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7 January 2021

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

1 reference

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7 January 2021

Origin of murine B cell lineages

1 reference

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7 January 2021

Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes

1 reference

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7 January 2021

Impaired expansion of mouse B cell progenitors lacking Btk.

1 reference

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7 January 2021

Defective B cell development and function in Btk-deficient mice

1 reference

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7 January 2021

The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

1 reference

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7 January 2021

A critical role of λ5 protein in B cell development

1 reference

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7 January 2021

A re‐evaluation of the effects of X‐linked immunodeficiency (xid) mutation on B cell differentiation and function in the mouse

1 reference

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7 January 2021

IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

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7 January 2021

Immunodeficiency in protein kinase cbeta-deficient mice

1 reference

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7 January 2021

Bclx regulates the survival of double-positive thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

B-cell receptor regulation of peripheral B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

The lymphocytes of splenic marginal zones: a distinct B-cell lineage

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Normal lymphocyte development but delayed humoral immune response in CD81-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

The surrogate light chain in B-cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Mutations in the human lambda5/14.1 gene result in B cell deficiency and agammaglobulinemia

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Normal development but differentially altered proliferative responses of lymphocytes in mice lacking CD81

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Antigen Receptor Signaling Gives Lymphocytes a Long Life

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

B lymphocytes are impaired in mice lacking the transcriptional co-activator Bob1/OCA-B/OBF1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Hyperresponsive B cells in CD22-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Population dynamics of bone marrow B lymphocytes.

1 reference

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7 January 2021

Murine B lymphopoiesis: towards a unified model

1 reference

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7 January 2021

CD22 regulates thymus-independent responses and the lifespan of B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

B lymphocytes may escape tolerance by revising their antigen receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Antigen receptors on B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

B-cell-specif ic coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Regulation of immune responses by NF-kappa B/Rel transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Transgene expression of bcl-xL permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

1 reference

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7 January 2021

Bar Mitzvah for B-1 cells: how will they grow up?

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7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Precursor B cells showing H chain allelic inclusion display allelic exclusion at the level of pre-B cell receptor surface expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Receptor editing in self-reactive bone marrow B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Aiolos regulates B cell activation and maturation to effector state

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Surface markers, heavy chain sequences and B cell lineages

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7 January 2021

Mutations in the mu heavy-chain gene in patients with agammaglobulinemia

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Treatment of murine CD5- B cells with anti-Ig, but not LPS, induces surface CD5: two B-cell activation pathways.

1 reference

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7 January 2021

Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980049-7

7 January 2021

10.1016/S1074-7613(00)80049-7

Identifiers

DOI

1 reference

28 July 2017

1 reference