Phylogenetic and functional analysis identifies Ets-1 as a novel regulator of the Th2 cytokine gene locus (Q33604211)

28 July 2017

title

Phylogenetic and functional analysis identifies Ets-1 as a novel regulator of the Th2 cytokine gene locus (English)

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28 July 2017

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Donata Vercelli

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28 July 2017

Jannine M Strempel

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28 July 2017

Roland Grenningloh

series ordinal

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28 July 2017

I-Cheng Ho

series ordinal

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28 July 2017

language of work or name

English

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publication date

28 December 2009

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28 July 2017

published in

Journal of Immunology

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28 July 2017

volume

184

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28 July 2017

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28 July 2017

page(s)

1309-1316

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Protective immune mechanisms in helminth infection

28 July 2017

cites work

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28 July 2018

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In silico identification of opossum cytokine genes suggests the complexity of the marsupial immune system rivals that of eutherian mammals

28 July 2018

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T helper cell differentiation: regulation by cis elements and epigenetics

28 July 2018

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28 July 2018

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Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking

28 July 2018

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28 July 2018

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28 July 2018

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Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.

28 July 2018

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Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors

28 July 2018

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The active spatial organization of the beta-globin locus requires the transcription factor EKLF

28 July 2018

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rVISTA 2.0: evolutionary analysis of transcription factor binding sites

28 July 2018

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

28 July 2018

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Identification of conserved regulatory elements by comparative genome analysis

28 July 2018

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Quantitative Estimates of Sequence Divergence for Comparative Analyses of Mammalian Genomes

28 July 2018

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Cytokine coexpression during human Th1/Th2 cell differentiation: direct evidence for coordinated expression of Th2 cytokines

28 July 2018

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Interleukin-13 gene expression is regulated by GATA-3 in T cells: role of a critical association of a GATA and two GATG motifs

28 July 2018

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Molecular phylogenetics and the origins of placental mammals

28 July 2018

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Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

28 July 2018

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Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1

28 July 2018

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The genomic record of Humankind's evolutionary roots

28 July 2018

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Interleukin-13: central mediator of allergic asthma

28 July 2018

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Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene

28 July 2018

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

28 July 2018

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Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

28 July 2018

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DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1

28 July 2018

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The activation domain of the bovine papillomavirus E2 protein mediates association of DNA-bound dimers to form DNA loops

28 July 2018

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Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif

28 July 2018

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A DNase I-hypersensitive site in the second intron of the murine IL-4 gene defines a mast cell-specific enhancer

28 July 2018

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Epigenetic control of T-helper-cell differentiation

28 July 2018

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Genome analysis of the platypus reveals unique signatures of evolution

30 October 2018

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Eosinophilic inflammation: mechanisms regulating IL-5 transcription in human T lymphocytes

30 October 2018

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A role for Ets1, synergizing with AP-1 and GATA-3 in the regulation of IL-5 transcription in mouse Th2 lymphocytes.

30 October 2018

1 reference

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Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses

30 October 2018

1 reference

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Characterization of the first nonmammalian T2 cytokine gene cluster: the cluster contains functional single-copy genes for IL-3, IL-4, IL-13, and GM-CSF, a gene for IL-5 that appears to be a pseudogene, and a gene encoding another cytokinelike trans

30 October 2018

1 reference

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Mulan: multiple-sequence local alignment and visualization for studying function and evolution

30 October 2018

1 reference

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Genomic clocks and evolutionary timescales

30 October 2018

1 reference

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T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809820

Deletion of a coordinate regulator of type 2 cytokine expression in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809820

An efficient cis-element discovery method using multiple sequence comparisons based on evolutionary relationships.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809820

Coordinate regulation of the IL-4, IL-13, and IL-5 cytokine cluster in Th2 clones revealed by allelic expression patterns

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809820

Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809820

A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells

30 October 2018

1 reference

12 December 2020

Regulation of the Th2 cytokine locus by a locus control region

1 reference

12 December 2020

Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus

1 reference

12 December 2020

Long-range intrachromosomal interactions in the T helper type 2 cytokine locus

1 reference

12 December 2020

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

1 reference

12 December 2020

Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region

1 reference

12 December 2020

Deletion of a conserved Il4 silencer impairs T helper type 1–mediated immunity

1 reference

12 December 2020

Infiltration of eosinophils into the asthmatic airways caused by interleukin 5

1 reference

12 December 2020

Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level

1 reference

12 December 2020

The Ets-1 transcription factor is required for the development of natural killer cells in mice

1 reference

12 December 2020

The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3

1 reference

12 December 2020

Susceptibility to Leishmania major infection in interleukin-4-deficient mice

1 reference

12 December 2020

Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0804162

1 reference

28 July 2017

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28 July 2017

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