Protein kinase C inhibitors: rationale for use and potential in the treatment of bipolar disorder (Q33573983)

28 July 2017

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title

Protein kinase C inhibitors: rationale for use and potential in the treatment of bipolar disorder (English)

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28 July 2017

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Husseini K Manji

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28 July 2017

Carlos A Zarate

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28 July 2017

publication date

1 January 2009

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

569-582

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Kinases as drug targets in the treatment of bipolar disorder

28 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Abnormalities in protein kinase C signaling and the pathophysiology of bipolar disorder

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Enhanced protein kinase C activity and translocation in bipolar affective disorder brains

21 June 2018

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21 June 2018

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21 June 2018

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Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: behavioral and in vivo microdialysis studies

21 June 2018

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21 June 2018

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Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity

21 June 2018

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21 June 2018

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Tamoxifen in the treatment of breast cancer

21 June 2018

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21 June 2018

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Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

21 June 2018

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Protein kinase C and dopamine transport--2. Effects of amphetamine in vitro

21 June 2018

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Protein kinase C and dopamine transport--1. Effects of amphetamine in vivo

21 June 2018

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A rating scale for mania: reliability, validity and sensitivity

21 June 2018

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21 June 2018

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21 June 2018

1 reference

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Clinical trials in bipolar mania: implications in study design and drug development

21 June 2018

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Protein kinase C inhibition by tamoxifen antagonizes manic-like behavior in rats: implications for the development of novel therapeutics for bipolar disorder.

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802274

Targeting the protein kinase C family: are we there yet?

31 October 2018

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A phase II study of carboplatin and chronic high-dose tamoxifen in patients with recurrent malignant glioma

31 October 2018

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Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.

31 October 2018

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Protein kinase C overactivity impairs prefrontal cortical regulation of working memory.

31 October 2018

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Intra-accumbens protein kinase C inhibitor NPC 15437 blocks amphetamine-produced conditioned place preference in rats

31 October 2018

1 reference

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Increased association of brain protein kinase C with the receptor for activated C kinase-1 (RACK1) in bipolar affective disorder

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802274

Injection of the protein kinase C inhibitor Ro31-8220 into the nucleus accumbens attenuates the acute response to amphetamine: tissue and behavioral studies

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802274

Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices

31 October 2018

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Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802274

Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802274

Increased dopamine and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: effects of diazepam

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802274

Intra-A10 injection of H7 blocks the development of sensitization to cocaine.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802274

Altered platelet protein kinase C activity in bipolar affective disorder, manic episode

31 October 2018

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12 December 2020

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

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12 December 2020

Clinical recognition and management of depression in node negative breast cancer patients treated with tamoxifen

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12 December 2020

Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine

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12 December 2020

Signaling through protein kinase C

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12 December 2020

Treatment-resistant bipolar disorder

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12 December 2020

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

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12 December 2020

Concurrent measures of protein kinase C and phosphoinositides in lithium-treated bipolar patients and healthy individuals: a preliminary study

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12 December 2020

Danazol and the rapid-cycling patient

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12 December 2020

Lithium inhibition of protein kinase C activation-induced serotonin release

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12 December 2020

Chronic Li+ attenuates agonist- and phorbol ester-mediated Na+/H+ antiporter activity in HL-60 cells

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12 December 2020

10.2165/00023210-200923070-00003

Identifiers

DOI

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Dimensions Publication ID

28 July 2017

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1 reference

28 July 2017

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