Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA. (Q33571121)

28 July 2017

title

Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA. (English)

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Mycobacterium tuberculosis

28 July 2017

main subject

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author name string

Katherine A Rawls

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28 July 2017

P Therese Lang

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28 July 2017

Jun Takeuchi

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28 July 2017

Shinichi Imamura

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28 July 2017

Tyler D Baguley

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28 July 2017

Christoph Grundner

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28 July 2017

Tom Alber

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28 July 2017

Jonathan A Ellman

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28 July 2017

language of work or name

English

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publication date

25 October 2009

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Bioorganic & Medicinal Chemistry Letters

28 July 2017

published in

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

6851-6854

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A balancing act: efflux/influx in mycobacterial drug resistance

28 July 2017

cites work

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21 June 2018

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21 June 2018

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Protein tyrosine phosphatase PtpA is not required for Mycobacterium tuberculosis growth in mice

21 June 2018

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Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor

21 June 2018

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Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B

21 June 2018

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Identification of a new class of nonpeptidic inhibitors of cruzain

21 June 2018

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Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode

21 June 2018

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PTP1B as a drug target: recent developments in PTP1B inhibitor discovery

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach

21 June 2018

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21 June 2018

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Crystal structure of low-molecular-weight protein tyrosine phosphatase from Mycobacterium tuberculosis at 1.9-A resolution

21 June 2018

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21 June 2018

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A specific mechanism of nonspecific inhibition

21 June 2018

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Expression and localization of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Synthetic chalcones as efficient inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

21 June 2018

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Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB.

31 October 2018

1 reference

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Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method

31 October 2018

1 reference

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Screening-based discovery and structural dissection of a novel family 18 chitinase inhibitor

31 October 2018

1 reference

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Rapid identification of potent nonpeptidic serine protease inhibitors

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19889539

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2009.10.090

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28 July 2017

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28 July 2017

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