Leptin in immuno-rheumatological diseases (Q33577477)

28 July 2017

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title

Leptin in immuno-rheumatological diseases (English)

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28 July 2017

Luca Navarini

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Marta Vadacca

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28 July 2017

Domenico P E Margiotta

series ordinal

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28 July 2017

Antonella Afeltra

series ordinal

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28 July 2017

publication date

14 March 2011

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Cellular and Molecular Immunology

28 July 2017

published in

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

203-212

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Role of leptin in the activation of immune cells.

28 July 2017

cites work

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Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis.

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21 June 2018

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The intricate interface between immune and metabolic regulation: a role for leptin in the pathogenesis of multiple sclerosis?

21 June 2018

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Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis

21 June 2018

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Leptin in autoimmunity: many questions, some answers

21 June 2018

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The emerging role of adipokines as mediators of inflammation and immune responses

21 June 2018

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21 June 2018

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21 June 2018

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Involvement of leptin signaling in the survival and maturation of bone marrow-derived dendritic cells.

21 June 2018

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Leptin inhibits apoptosis in thymus through a janus kinase-2-independent, insulin receptor substrate-1/phosphatidylinositol-3 kinase-dependent pathway.

21 June 2018

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Control of GnRH neuronal activity by metabolic factors: the role of leptin and insulin

21 June 2018

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Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

21 June 2018

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Recent advances in the relationship between obesity, inflammation, and insulin resistance.

21 June 2018

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Ubiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Defining the role of T cell-derived leptin in the modulation of hepatic or intestinal inflammation in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Adipose tissue, adipokines, and inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

21 June 2018

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Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin receptor expression on T lymphocytes modulates chronic intestinal inflammation in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Possible role of leptin in hypoandrogenicity in patients with systemic lupus erythematosus and rheumatoid arthritis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

The weight of leptin in immunity

21 June 2018

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Obese, a new mutation in the house mouse

21 June 2018

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Obesity wars: molecular progress confronts an expanding epidemic

21 June 2018

1 reference

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Leptin-deficient mice are protected from accelerated nephrotoxic nephritis

21 June 2018

1 reference

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The role of depot fat in the hypothalamic control of food intake in the rat.

21 June 2018

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21 June 2018

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Leptin consumption in the inflamed joints of patients with rheumatoid arthritis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

A role for leptin in rheumatic diseases?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Role of leptin as an immunomodulator of blood mononuclear cells: mechanisms of action

21 June 2018

1 reference

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Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Serum leptin levels in women with systemic lupus erythematosus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin deficiency, not obesity, protects mice from Con A-induced hepatitis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Requirement for leptin in the induction and progression of autoimmune encephalomyelitis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin in the regulation of immunity, inflammation, and hematopoiesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Central nervous system control of food intake

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin serum levels are not correlated with disease activity in patients with rheumatoid arthritis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

A short form of leptin receptor performs signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Serum leptin concentrations in human immunodeficiency virus-infected men with low adiposity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

A role for leptin and its cognate receptor in hematopoiesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Identification and expression cloning of a leptin receptor, OB-R

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Positional cloning of the mouse obese gene and its human homologue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Weight-reducing effects of the plasma protein encoded by the obese gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Effects of the obese gene product on body weight regulation in ob/ob mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Threading analysis suggests that the obese gene product may be a helical cytokine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Adipsin and complement factor D activity: an immune-related defect in obesity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation

21 June 2018

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Regulation of leptin gene expression by insulin and growth hormone in mouse adipocytes

21 January 2018

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Obesity: Causes and control of excess body fat.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCMI.2010.75

Elevated serum leptin concentrations induced by experimental acute inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2010.75

Involvement of plasma leptin, insulin and free tryptophan in cytokine-induced anorexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2010.75

Decreased CD4+ lymphocyte activation and increased interleukin-4 production in peripheral blood of rheumatoid arthritis patients after acute starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2010.75

Pro-inflammatory effect of leptin on peripheral blood mononuclear cells of patients with ankylosing spondylitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2010.75

Insulin sensitivity and related cytokines, chemokines, and adipokines in polymyalgia rheumatica

21 January 2018

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https://api.crossref.org/works/10.1038%2FCMI.2010.75

Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012876

Induction of Neutrophil Chemotaxis by Leptin: Crucial Role for p38 and Src Kinases

31 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2010.75

Leptin and ghrelin in Korean systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2010.75

Serum adipokine levels in patients with systemic lupus erythematosus

21 January 2018

1 reference

12 December 2020

Psoriasis arthropathica associated with severe obesity showing high serum leptin level

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12 December 2020

Leptin serum levels in rheumatoid arthritis patients: relation to disease duration and activity

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12 December 2020

Effects of parabiosis of obese with diabetes and normal mice

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12 December 2020

Leptin as a marker of multiple sclerosis activity in patients treated with interferon-beta

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12 December 2020

Serum leptin in systemic lupus erythematosus

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12 December 2020

Leptin accelerates autoimmune diabetes in female NOD mice

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12 December 2020

A decreased serum leptin level in patients with systemic sclerosis

1 reference

12 December 2020

Leptin receptor expression and signaling in lymphocytes: kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice

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12 December 2020

Adipokines and systemic lupus erythematosus: relationship with metabolic syndrome and cardiovascular disease risk factors

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12 December 2020

Leptin Promotes Differentiation and Survival of Human Dendritic Cells and Licenses Them for Th1 Priming

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12 December 2020

A key role of leptin in the control of regulatory T cell proliferation

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12 December 2020

Adipose tissue, serum adipokines, and ghrelin in patients with ankylosing spondylitis

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12 December 2020

Identifiers

DOI

10.1038/CMI.2010.75

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference