Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK (Q33562476)

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English	Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 July 2017

Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Randall J Kimple

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Randall J Kimple

3

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author name string

Maria J Sambade

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

J Terese Camp

2

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Europe PubMed Central

PubMed publication ID

28 July 2017

Carolyn I Sartor

4

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Europe PubMed Central

PubMed publication ID

28 July 2017

Janiel M Shields

5

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Europe PubMed Central

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28 July 2017

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23 October 2009

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Europe PubMed Central

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28 July 2017

Radiotherapy and Oncology

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Europe PubMed Central

PubMed publication ID

28 July 2017

93

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Europe PubMed Central

PubMed publication ID

28 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

639-644

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

EGFR-directed therapies to treat non-small-cell lung cancer

1 reference

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1 reference

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1 reference

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Principles of cancer therapy: oncogene and non-oncogene addiction

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ErbB receptors and signaling pathways in cancer

1 reference

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Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

1 reference

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FDA drug approval summary: lapatinib in combination with capecitabine for previously treated metastatic breast cancer that overexpresses HER-2.

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Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer

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EGFR-targeted anti-cancer drugs in radiotherapy: preclinical evaluation of mechanisms

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Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

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14 July 2018

Mechanisms of disease: Radiosensitization by epidermal growth factor receptor inhibitors

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Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway

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In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody

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12 December 2020

based on heuristic

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Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19853943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Anti-EGFR and radiotherapy]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19853943

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.RADONC.2009.09.006

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

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