cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor (Q33554709)

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English	cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor	scientific article

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scholarly article

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Europe PubMed Central

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28 July 2017

cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor (English)

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28 July 2017

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Masahiro Fujita

1

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2 June 2020

3

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2 June 2020

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E M Richards

2

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2 June 2020

D F Ionescu

4

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2 June 2020

S S Zoghbi

5

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2 June 2020

J Hong

6

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2 June 2020

S Telu

7

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2 June 2020

C S Hines

8

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2 June 2020

V W Pike

9

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2 June 2020

C A Zarate

10

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2 June 2020

R B Innis

11

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2 June 2020

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publication date

11 October 2016

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28 July 2017

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6

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Molecular Psychiatry

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2 June 2020

22

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2 June 2020

5

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2 June 2020

754-759

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27725657%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Phosphodiesterase-4 modulation as a potential therapeutic for cognitive loss in pathological and non-pathological aging: possibilities and pitfalls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

DISC1 as a therapeutic target for mental illnesses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Downregulation of brain phosphodiesterase type IV measured with 11C-(R)-rolipram positron emission tomography in major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Kinetic analysis in human brain of [11C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: a retest study and use of an image-derived input function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

The human area postrema and other nuclei related to the emetic reflex express cAMP phosphodiesterases 4B and 4D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Effects of cAMP-dependent protein kinase activator and inhibitor on in vivo rolipram binding to phosphodiesterase 4 in conscious rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

PET measurement of the in vivo affinity of 11C-(R)-rolipram and the density of its target, phosphodiesterase-4, in the brains of conscious and anesthetized rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Consensus nomenclature for in vivo imaging of reversibly binding radioligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

A rating scale for depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

The assessment of anxiety states by rating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Synaptic plasticity and mood disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Brain [3H]cAMP binding sites are unaltered in depressed suicides, but decreased by antidepressants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

In-patient major depression: is rolipram as effective as amitriptyline?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

A New Depression Scale Designed to be Sensitive to Change

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

21 June 2018

Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Increased temporal cortex CREB concentrations and antidepressant treatment in major depression

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Brain volume abnormalities in major depressive disorder: a meta-analysis of magnetic resonance imaging studies

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjects

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Reduced phosphorylation of cyclic AMP-responsive element binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Gene expression and association analyses of the phosphodiesterase 4B (PDE4B) gene in major depressive disorder in the Japanese population

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Interaction of metoprolol with lorazepam and bromazepam

1 reference

https://api.crossref.org/works/10.1038%2FMP.2016.171

21 January 2018

Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5388600

31 October 2018

Rolipram versus imipramine in inpatients with major, "minor" or atypical depressive disorder: a double-blind double-dummy study aimed at testing a novel therapeutic approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/27725657

12 December 2020

based on heuristic

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Reduced adenylyl cyclase immunolabeling and activity in postmortem temporal cortex of depressed suicide victims

1 reference

https://pubmed.ncbi.nlm.nih.gov/27725657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[(3)H]cAMP binding sites and protein kinase a activity in the prefrontal cortex of suicide victims

1 reference

https://pubmed.ncbi.nlm.nih.gov/27725657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Results of a phase II study of the antidepressant effect of rolipram

1 reference

https://pubmed.ncbi.nlm.nih.gov/27725657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and Biochemical Effects of the Selective Phosphodiesterase Inhibitor Rolipram in Depressed Inpatients Controlled by Determination of Plasma Level

1 reference

https://pubmed.ncbi.nlm.nih.gov/27725657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/MP.2016.171

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27725657%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

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2 June 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27725657%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

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