Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer (Q33463860)

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English	Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 July 2017

Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer (English)

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Europe PubMed Central

PubMed publication ID

27 July 2017

DNA methylation

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Curt Balch

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Europe PubMed Central

PubMed publication ID

27 July 2017

Kenneth P Nephew

9

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Kenneth P Nephew

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27 July 2017

author name string

Meng Li

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27 July 2017

John S Montgomery

3

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27 July 2017

Mikyoung Jeong

4

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27 July 2017

Jae Hoon Chung

5

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27 July 2017

Pearlly Yan

6

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27 July 2017

Tim H M Huang

7

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27 July 2017

Sun Kim

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27 July 2017

publication date

8 June 2009

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27 July 2017

BMC Medical Genomics

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27 July 2017

2

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Europe PubMed Central

PubMed publication ID

27 July 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712480

21 June 2018

Carboplatin-induced gene expression changes in vitro are prognostic of survival in epithelial ovarian cancer

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21 June 2018

A genomic approach to identify molecular pathways associated with chemotherapy resistance

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21 June 2018

DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage

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21 June 2018

Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands

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21 June 2018

Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma.

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21 June 2018

Enriched transcription factor binding sites in hypermethylated gene promoters in drug resistant cancer cells

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21 June 2018

DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells

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21 June 2018

High definition cytogenetics and oligonucleotide aCGH analyses of cisplatin-resistant ovarian cancer cells

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21 June 2018

Regulation of the CLDN3 gene in ovarian cancer cells

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21 June 2018

Cancer epigenetics: modifications, screening, and therapy

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21 June 2018

Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer

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21 June 2018

A systems biology approach for pathway level analysis

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21 June 2018

The resurgence of platinum-based cancer chemotherapy

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21 June 2018

Claudin-4 overexpression in epithelial ovarian cancer is associated with hypomethylation and is a potential target for modulation of tight junction barrier function using a C-terminal fragment of Clostridium perfringens enterotoxin

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21 June 2018

Resistance to TGF-beta 1 correlates with aberrant expression of TGF-beta receptor II in human B-cell lymphoma cell lines

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21 June 2018

Mechanisms of resistance to cisplatin and carboplatin

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21 June 2018

The epigenomics of cancer

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21 June 2018

An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.

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21 June 2018

Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

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21 June 2018

Identification of platinum-resistance associated proteins through proteomic analysis of human ovarian cancer cells and their platinum-resistant sublines

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21 June 2018

Biochemical mechanisms of cisplatin cytotoxicity

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21 June 2018

Clinical relevance of E2F family members in ovarian cancer--an evaluation in a training set of 77 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712480

21 June 2018

Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712480

21 June 2018

DNA-methylation-dependent alterations of claudin-4 expression in human bladder carcinoma.

1 reference

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21 June 2018

Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712480

21 June 2018

Analysis of gene expression in pathophysiological states: balancing false discovery and false negative rates

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21 June 2018

Exploiting the PI3K/AKT pathway for cancer drug discovery

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21 June 2018

Proteins associated with Cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels

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21 June 2018

Claudin proteins in human cancer: promising new targets for diagnosis and therapy

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21 June 2018

Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer

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21 June 2018

Cancer chemotherapy by deoxynucleotide depletion and E2F-1 elevation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712480

21 June 2018

Mammalian tight junctions in the regulation of epithelial differentiation and proliferation

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21 June 2018

Recruitment of DNA methyltransferase I to DNA repair sites

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21 June 2018

Treatment goals in ovarian cancer

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21 June 2018

New anti-cancer strategies: epigenetic therapies and biomarkers

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21 June 2018

Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers

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21 June 2018

The epigenetics of ovarian cancer drug resistance and resensitization

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21 June 2018

Bioconductor: open software development for computational biology and bioinformatics

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21 June 2018

The history of cancer epigenetics

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21 June 2018

Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells

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21 June 2018

Strategies for reversing drug resistance

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21 June 2018

Cisplatin: mode of cytotoxic action and molecular basis of resistance

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21 June 2018

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21 June 2018

Ovarian cancer: strategies for overcoming resistance to chemotherapy

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21 June 2018

DAVID: Database for Annotation, Visualization, and Integrated Discovery

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21 June 2018

Molecular description of evolving paclitaxel resistance in the SKOV-3 human ovarian carcinoma cell line

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21 June 2018

Signalling to and from tight junctions

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21 June 2018

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21 June 2018

Analysis of gene expression profiles associated with cisplatin resistance in human ovarian cancer cell lines and tissues using cDNA microarray.

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21 June 2018

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

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21 June 2018

Altered adhesion properties and alphav integrin expression in a cisplatin-resistant human ovarian carcinoma cell line.

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21 June 2018

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21 June 2018

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

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21 June 2018

A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer

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21 June 2018

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21 June 2018

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21 June 2018

hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents

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21 June 2018

Comparative genomic hybridization analysis of chromosomal changes occurring during development of acquired resistance to cisplatin in human ovarian carcinoma cells

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21 June 2018

Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance

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21 June 2018

Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer

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21 June 2018

Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells

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21 June 2018

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

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28 July 2018

Prognostic DNA methylation biomarkers in ovarian cancer.

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21 January 2018

The control of the false discovery rate in multiple testing under dependency

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21 January 2018

Drug reactivates genes to inhibit cancer

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21 January 2018

Clinical development of platinum complexes in cancer therapy: an historical perspective and an update.

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21 January 2018

Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells.

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21 January 2018

DNA methylation in ovarian cancer. II. Expression of DNA methyltransferases in ovarian cancer cell lines and normal ovarian epithelial cells

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21 January 2018

Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells.

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21 January 2018

alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells

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21 January 2018

Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation?

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21 January 2018

Gonadotropins regulate N-cadherin-mediated human ovarian surface epithelial cell survival at both post-translational and transcriptional levels through a cyclic AMP/protein kinase A pathway

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21 January 2018

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability

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31 October 2018

Aberrant DNA methylation in ovarian cancer: is there an epigenetic predisposition to drug response?

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12 December 2020

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Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues

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12 December 2020

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Possible involvement of hMLH1, p16(INK4a) and PTEN in the malignant transformation of endometriosis

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12 December 2020

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Applications of CpG island microarrays for high-throughput analysis of DNA methylation

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Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers

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12 December 2020

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Differential methylation hybridization using CpG island arrays

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12 December 2020

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Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer

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12 December 2020

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Epigenetic profiling of multidrug-resistant human MCF-7 breast adenocarcinoma cells reveals novel hyper- and hypomethylated targets

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12 December 2020

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CpG Island Methylation of DNA Damage Response Genes in Advanced Ovarian Cancer

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12 December 2020

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Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter

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10.1186/1755-8794-2-34

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Europe PubMed Central

PubMed publication ID

27 July 2017

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/1755-8794-2-34

9 September 2019

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

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