Novel GMP-compatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells. (Q33456264)

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6 March 2020

title

Novel GMP-compatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells (English)

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6 March 2020

author

Sybille Landwehr-Kenzel

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6 March 2020

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6 March 2020

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6 March 2020

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6 March 2020

S-H Luu

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6 March 2020

M Schmück

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6 March 2020

H Lei

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6 March 2020

A Zobel

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6 March 2020

A Thiel

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6 March 2020

N Babel

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6 March 2020

K Wood

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6 March 2020

language of work or name

English

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publication date

27 January 2014

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American Journal of Transplantation

6 March 2020

published in

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volume

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issue

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page(s)

594-606

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

6 March 2020

cites work

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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Regulatory T cells in transplantation tolerance

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Regulatory immune cells in transplantation

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Permanent CNI treatment for prevention of renal allograft rejection in sensitized hosts can be replaced by regulatory T cells

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Abnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion model

21 January 2018

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Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity

21 January 2018

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Clinical perspectives for regulatory T cells in transplantation tolerance

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Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells.

21 January 2018

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Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation

21 January 2018

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Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells

21 January 2018

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Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

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Treatment of graft-versus-host disease with naturally occurring T regulatory cells

21 January 2018

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Efficient induction and expansion of human alloantigen-specific CD8 regulatory T cells from naive precursors by CD40-activated B cells.

21 January 2018

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CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4(+) regulatory T cells

21 January 2018

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Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells

21 January 2018

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Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells

21 January 2018

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A converse 4-1BB and CD40 ligand expression pattern delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+ Treg.

21 January 2018

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Gene and haplotype frequencies for the loci hLA-A, hLA-B, and hLA-DR based on over 13,000 german blood donors

21 January 2018

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Identification of dialysis patients with panel-reactive memory T cells before kidney transplantation using an allogeneic cell bank

21 January 2018

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Conditional immortalization of human B cells by CD40 ligation

21 January 2018

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Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells

21 January 2018

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Deep sequencing of the human TCRγ and TCRβ repertoires suggests that TCRβ rearranges after αβ and γδ T cell commitment

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IMGT/JunctionAnalysis: the first tool for the analysis of the immunoglobulin and T cell receptor complex V-J and V-D-J JUNCTIONs

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Multiple unit pooled umbilical cord blood is a viable source of therapeutic regulatory T cells.

21 January 2018

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Homing of regulatory T cells to human skin is important for the prevention of alloimmune-mediated pathology in an in vivo cellular therapy model

21 January 2018

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Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model.

21 January 2018

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T-cell antigen receptor genes and T-cell recognition

21 January 2018

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High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets

21 January 2018

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How many mechanisms do regulatory T cells need?

21 January 2018

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A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.

21 January 2018

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Regulatory T cells for the prevention of graft-versus-host disease: professionals defeat amateurs.

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The potency of allospecific Tregs cells appears to correlate with T cell receptor functional avidity.

21 January 2018

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Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation.

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TCR repertoire analysis by next generation sequencing allows complex differential diagnosis of T cell-related pathology.

21 January 2018

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Immunological unresponsiveness induced by recipient cells transfected with donor MHC genes.

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21 January 2018

Identifiers

DOI

10.1111/AJT.12629

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6 March 2020

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