Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma (Q33400356)

26 July 2017

title

Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma (English)

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26 July 2017

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Trudy F C Mackay

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26 July 2017

Robert R H Anholt

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26 July 2017

Mary Anna Carbone

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26 July 2017

Julien F Ayroles

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26 July 2017

Akihiko Yamamoto

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26 July 2017

Tatiana V Morozova

series ordinal

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26 July 2017

Steven A West

series ordinal

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26 July 2017

Michael M Magwire

series ordinal

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26 July 2017

language of work or name

English

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publication date

16 January 2009

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26 July 2017

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26 July 2017

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26 July 2017

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26 July 2017

page(s)

e4216

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Creative Commons Attribution 4.0 International

26 July 2017

start time

16 January 2009

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

affy

object named as

Affy package

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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21 June 2018

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Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

21 June 2018

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Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells

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Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC).

21 June 2018

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Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor

21 June 2018

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A Drosophila model of Parkinson's disease

21 June 2018

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21 June 2018

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Identification of a new ‘TIGR’ mutation in a family with juvenile-onset primary open angle glaucoma

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21 June 2018

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Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma

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21 January 2018

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Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

21 January 2018

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Recurrent Mutations in a Single Exon Encoding the Evolutionarily Conserved Olfactomedin-Homology Domain of TIGR in Familial Open-Angle Glaucoma

21 January 2018

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Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A)

21 January 2018

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Analysis of myocilin mutations in 1703 glaucoma patients from five different populations

21 January 2018

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Homozygotes carrying an autosomal dominant TIGR mutation do not manifest glaucoma

21 January 2018

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Noelins modulate the timing of neuronal differentiation during development

21 January 2018

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Immunolocalization of myocilin protein in the anterior eye of normal and primary open-angle glaucomatous dogs

21 January 2018

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Expression of mutated mouse myocilin induces open-angle glaucoma in transgenic mice.

21 January 2018

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Founder mutations of CYP1B1 gene in patients with congenital glaucoma from the United States and Brazil

21 January 2018

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Novel cytochrome P450 1B1 (CYP1B1) mutations in patients with primary congenital glaucoma in France

21 January 2018

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A protocol for dissecting Drosophila melanogaster brains for live imaging or immunostaining

21 January 2018

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Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish

21 January 2018

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Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure.

31 October 2018

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GAL4 causes developmental defects and apoptosis when expressed in the developing eye of Drosophila melanogaster.

31 October 2018

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Soluble guanylate cyclase is required during development for visual system function in Drosophila.

31 October 2018

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Prevalence of myocilin mutations in adults with primary open-angle glaucoma in Ghana, West Africa

31 October 2018

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12 December 2020

Inefficient processing of an olfactomedin-deficient myocilin mutant: potential physiological relevance to glaucoma

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12 December 2020

Novel trabecular meshwork inducible glucocorticoid response mutation in an eight-generation juvenile-onset primary open-angle glaucoma pedigree

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Mutation spectrum of the CYP1B1 gene in Indian primary congenital glaucoma patients

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Heterozygous CYP1B1 gene mutations in Spanish patients with primary open-angle glaucoma

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Recent developments in understanding the pathophysiology of elevated intraocular pressure

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Intracellular sequestration of hetero-oligomers formed by wild-type and glaucoma-causing myocilin mutants

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Aqueous humor myocilin protein levels in normal, genetic carriers, and glaucoma Beagles

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12 December 2020

Primary role of CYP1B1 in Indian juvenile-onset POAG patients

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12 December 2020

10.1371/JOURNAL.PONE.0004216

Identifiers

DOI

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26 July 2017

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26 July 2017

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