Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites (Q33404454)

26 July 2017

title

Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites (English)

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26 July 2017

Allison A Burrow

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26 July 2017

Laura E Williams

series ordinal

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26 July 2017

Levi C T Pierce

series ordinal

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26 July 2017

Yuh-Hwa Wang

series ordinal

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26 July 2017

language of work or name

English

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publication date

30 January 2009

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26 July 2017

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26 July 2017

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26 July 2017

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Cytogenetic biomarkers for human cancer

26 July 2017

cites work

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Replication stress induces tumor-like microdeletions in FHIT/FRA3B

21 June 2018

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The role of chromosomal alterations in human cancer development

21 June 2018

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An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae

21 June 2018

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21 June 2018

Chromosome fragile sites

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Cloning of genetically tagged chromosome break sequences reveals new fragile sites at 6p21 and 13q22.

21 June 2018

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TICdb: a collection of gene-mapped translocation breakpoints in cancer

21 June 2018

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Large common fragile site genes and cancer

21 June 2018

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21 June 2018

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Common fragile sites as targets for chromosome rearrangements

21 June 2018

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Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability

21 June 2018

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Common chromosomal fragile sites and cancer: focus on FRA16D.

21 June 2018

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BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function

21 June 2018

1 reference

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Molecular basis for expression of common and rare fragile sites

21 June 2018

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Mfold web server for nucleic acid folding and hybridization prediction

21 June 2018

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Genetic alterations in cancer as a result of breakage at fragile sites

21 June 2018

1 reference

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ATR Regulates Fragile Site Stability

21 June 2018

1 reference

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The DNA replication checkpoint response stabilizes stalled replication forks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Fragile and unstable chromosomes in cancer: causes and consequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Replication delay along FRA7H, a common fragile site on human chromosome 7, leads to chromosomal instability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Molecular mechanisms of DNA double strand break repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

A breakpoint map of recurrent chromosomal rearrangements in human neoplasia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Constitutive fragile sites and cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Initiation of SV40 DNA replication in vivo: Location and structure of 5′ ends of DNA synthesized in the ori region

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Metabolism of Okazaki fragments during simian virus 40 DNA replication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Mechanistic aspects of lymphoid chromosomal translocations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Interplay between ATM and ATR in the regulation of common fragile site stability

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

31 October 2018

Common fragile sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Characterization of a conserved aphidicolin-sensitive common fragile site at human 4q22 and mouse 6C1: possible association with an inherited disease and cancer

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

RET rearrangements in radiation-induced papillary thyroid carcinomas: high prevalence of topoisomerase I sites at breakpoints and microhomology-mediated end joining in ELE1 and RET chimeric genes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Rejoining of DNA double-strand breaks in vitro by single-strand annealing

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

Variation in the expression of aphidicolin-induced fragile sites in human lymphocyte cultures

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2642838

The expression of fragile sites in lymphocytes of patients with rectum cancer and their first-degree relatives

31 October 2018

1 reference

12 December 2020

Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction

1 reference

12 December 2020

Analysis of replication timing at the FRA10B and FRA16B fragile site loci

1 reference

12 December 2020

New heritable fragile site at 15q13 in both members of a nonconsanguineous couple

1 reference

12 December 2020

Fragile sites still breaking

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2164-10-59

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Dimensions Publication ID

26 July 2017

0 references

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26 July 2017

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