Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance (Q33382292)

26 July 2017

title

Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance (English)

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26 July 2017

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Stacey L Hembruff

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26 July 2017

Monique L Laberge

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26 July 2017

David J Villeneuve

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26 July 2017

Baoqing Guo

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26 July 2017

Zachary Veitch

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26 July 2017

Melanie Cecchetto

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26 July 2017

Amadeo M Parissenti

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26 July 2017

language of work or name

English

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publication date

3 November 2008

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26 July 2017

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26 July 2017

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26 July 2017

page(s)

318

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The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

26 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A.

21 June 2018

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21 June 2018

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Mrp4 confers resistance to topotecan and protects the brain from chemotherapy

21 June 2018

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Cross-resistance studies of isogenic drug-resistant breast tumor cell lines support recent clinical evidence suggesting that sensitivity to paclitaxel may be strongly compromised by prior doxorubicin exposure

21 June 2018

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Potent killing of paclitaxel- and doxorubicin-resistant breast cancer cells by calphostin C accompanied by cytoplasmic vacuolization

21 June 2018

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Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.

21 June 2018

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Vaults: a ribonucleoprotein particle involved in drug resistance?

21 June 2018

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Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA.

21 June 2018

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Multidrug resistance in cancer: role of ATP-dependent transporters

21 June 2018

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The human ATP-binding cassette (ABC) transporter superfamily

21 June 2018

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Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

21 June 2018

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Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines

21 June 2018

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P-glycoprotein expression on normal and abnormally expanded natural killer cells and inhibition of P-glycoprotein function by cyclosporin A and its analogue, PSC833.

21 June 2018

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Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell

21 June 2018

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21 June 2018

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A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation

21 June 2018

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Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex

21 June 2018

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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

21 June 2018

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Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection.

21 June 2018

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Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines

21 June 2018

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P-glycoprotein immunostaining correlates with ER and with high Ki67 expression but fails to predict anthracycline resistance in patients with advanced breast cancer

21 June 2018

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https://api.crossref.org/works/10.1186%2F1471-2407-8-318

Cells from chronic myelogenous leukaemia patients at presentation exhibit multidrug resistance not mediated by either MDR1 or MRP1.

21 January 2018

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The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis

21 January 2018

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https://api.crossref.org/works/10.1186%2F1471-2407-8-318

cDNA microarray analysis of isogenic paclitaxel- and doxorubicin-resistant breast tumor cell lines reveals distinct drug-specific genetic signatures of resistance.

21 January 2018

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Pharmacokinetics of doxorubicin administered i.v. as Myocet (TLC D-99; liposome-encapsulated doxorubicin citrate) compared with conventional doxorubicin when given in combination with cyclophosphamide in patients with metastatic breast cancer

21 January 2018

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Inhibition study of rabbit liver cytosolic reductases involved in daunorubicin toxication

21 January 2018

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Overcoming the classical multidrug resistance phenotype by adenoviral delivery of anti-MDR1 short hairpin RNAs and ribozymes.

21 January 2018

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Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

31 October 2018

1 reference

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Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596802

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells

31 October 2018

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Ninety-six-hour paclitaxel infusion after progression during short taxane exposure: a phase II pharmacokinetic and pharmacodynamic study in metastatic breast cancer

31 October 2018

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12 December 2020

Low-level doxorubicin resistance in benzo[a]pyrene-treated KB-3-1 cells is associated with increased LRP expression and altered subcellular drug distribution

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12 December 2020

PAC fixed dose: pharmacokinetics of a 1-hour paclitaxel infusion and comparison to BSA-normalized drug dosing

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12 December 2020

Pharmacokinetics and toxicity of two schedules of high dose epirubicin

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12 December 2020

Expression of drug resistance proteins in breast cancer, in relation to chemotherapy

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12 December 2020

Identifiers

DOI

10.1186/1471-2407-8-318

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Dimensions Publication ID

26 July 2017

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26 July 2017

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