Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1. (Q33325766)

25 July 2017

title

Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1. (English)

1 reference

25 July 2017

Juan Galceran

0 references

Walter Becker

0 references

Barbara Maenz

1 reference

25 July 2017

Paul Hekerman

series ordinal

1 reference

25 July 2017

Eva M Vela

series ordinal

1 reference

25 July 2017

publication date

26 March 2008

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25 July 2017

published in

BMC Molecular Biology

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25 July 2017

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25 July 2017

1 reference

High-resolution profiling of histone methylations in the human genome

25 July 2017

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DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding

21 June 2018

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Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

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21 June 2018

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21 June 2018

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21 June 2018

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Microenvironment-driven changes in the expression profile of hematopoietic cobblestone area-forming cells

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice

21 June 2018

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Experimental analysis of the annotation of promoters in the public database

21 June 2018

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Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1

21 June 2018

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Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions.

21 June 2018

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A 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinase

21 June 2018

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Identification of novel E2F1-regulated genes by microarray

21 June 2018

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21 June 2018

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21 June 2018

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Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A

21 June 2018

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A transcriptionally inactive E2F-1 targets the MDM family of proteins for proteolytic degradation

21 June 2018

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Transcriptional regulation by the phosphorylation-dependent factor CREB

21 June 2018

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RNA expression patterns change dramatically in human neutrophils exposed to bacteria

21 June 2018

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Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division

21 June 2018

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E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 June 2018

1 reference

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REDK, a novel human regulatory erythroid kinase

21 June 2018

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Activation changes the spectrum but not the diversity of genes expressed by T cells.

21 June 2018

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Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

Identification of two novel 5' noncoding exons in human MNB/DYRK gene and alternatively spliced transcripts

21 June 2018

1 reference

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p14ARF links the tumour suppressors RB and p53.

21 June 2018

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21 June 2018

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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila

21 June 2018

1 reference

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Acute-Phase Response Factor, a Nuclear Factor Binding to Acute-Phase Response Elements, is Rapidly Activated by Interleukin-6 at the Posttranslational Level

21 June 2018

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Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome

21 June 2018

1 reference

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Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells

21 June 2018

1 reference

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Dopaminergic deficiency in mice with reduced levels of the dual-specificity tyrosine-phosphorylated and regulated kinase 1A, Dyrk1A(+/-).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/- mouse

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

Coordinate activation of maternal protein degradation during the egg-to-embryo transition in C. elegans

31 October 2018

1 reference

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Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells

31 October 2018

1 reference

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Differentially expressed genes identified in human melanoma cell lines with different metastatic behaviour using high density oligonucleotide arrays

31 October 2018

1 reference

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Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

YakA, a protein kinase required for the transition from growth to development in Dictyostelium.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292204

Familial 4.3 Mb duplication of 21q22 sheds new light on the Down syndrome critical region

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18366763

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The N-terminal region of E2F-1 is required for transcriptional activation of a new class of target promoter

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18366763

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2199-9-30

1 reference

Dimensions Publication ID

25 July 2017

0 references

1 reference

25 July 2017

1 reference