PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice (Q33295459)

25 July 2017

title

PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice (English)

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25 July 2017

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Douglas R Cavener

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25 July 2017

Kaori Iida

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25 July 2017

Yulin Li

series ordinal

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25 July 2017

Barbara C McGrath

series ordinal

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25 July 2017

Ami Frank

series ordinal

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25 July 2017

publication date

29 August 2007

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25 July 2017

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25 July 2017

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25 July 2017

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ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice

25 July 2017

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21 June 2018

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Apoptosis versus necrosis in acute pancreatitis

21 June 2018

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Modes of Cell Death in Rat Liver after Monocrotaline Exposure

21 June 2018

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PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver

21 June 2018

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Necrosis: a specific form of programmed cell death?

21 June 2018

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21 June 2018

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Morphological and biochemical aspects of apoptosis, oncosis and necrosis

21 June 2018

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A critical evaluation of laboratory tests in acute pancreatitis

21 June 2018

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The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

21 June 2018

1 reference

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

21 June 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 June 2018

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Tamoxifen-induced severe hypertriglyceridemia and pancreatitis.

21 June 2018

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Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunity

21 June 2018

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EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

21 June 2018

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Perk is essential for translational regulation and cell survival during the unfolded protein response

21 June 2018

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 June 2018

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Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

21 June 2018

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Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases

21 June 2018

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Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

21 June 2018

1 reference

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Apoptosis, oncosis, and necrosis. An overview of cell death

21 June 2018

1 reference

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In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

21 June 2018

1 reference

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Diabetes mellitus and the exocrine pancreas

21 June 2018

1 reference

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Acute pancreatitis and normoamylasemia. Not an uncommon combination

21 June 2018

1 reference

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Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis

21 June 2018

1 reference

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Transforming growth factor-beta (TGF-beta 1) inhibits pancreatic acinar cell growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072952

Studies on the guinea pig pancreas. Parallel discharge of exocrine enzyme activities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072952

PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072952

Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis.

31 October 2018

1 reference

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Oncosis represents the main type of cell death in mouse models of cholestasis

31 October 2018

1 reference

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Caerulein-induced acute pancreatitis inhibits protein synthesis through effects on eIF2B and eIF4F.

31 October 2018

1 reference

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Cell-specific transgene expression from a widely transcribed promoter using Cre/lox in mice.

31 October 2018

1 reference

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Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice.

31 October 2018

1 reference

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Site- and time-specific gene targeting in the mouse

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072952

In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2072952

ER stress signaling by regulated splicing: IRE1/HAC1/XBP1

31 October 2018

1 reference

12 December 2020

Acinar cell apoptosis and the origin of tubular complexes in caerulein-induced pancreatitis

1 reference

12 December 2020

Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor

1 reference

12 December 2020

Wolcott-Rallison syndrome: a case with endocrine and exocrine pancreatic deficiency and pancreatic hypotrophy

1 reference

12 December 2020

NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response

1 reference

12 December 2020

Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice

1 reference

12 December 2020

Specific expression of an elastase–human growth hormone fusion gene in pancreatic acinar cells of transgenic mice

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2121-8-38

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Dimensions Publication ID

25 July 2017

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25 July 2017

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