Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly. (Q33280963)

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28 December 2019

title

Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly (English)

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28 December 2019

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28 December 2019

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28 December 2019

J Keith Joung

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28 December 2019

David A Wright

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28 December 2019

Stacey Thibodeau-Beganny

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28 December 2019

Jeffry D Sander

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28 December 2019

Ronnie J Winfrey

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28 December 2019

Andrew S Hirsh

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28 December 2019

Magdalena Eichtinger

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28 December 2019

Fengli Fu

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28 December 2019

Matthew H Porteus

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28 December 2019

publication date

1 January 2006

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28 December 2019

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28 December 2019

volume

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issue

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28 December 2019

page(s)

1637-1652

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Efficient gene targeting in Drosophila with zinc-finger nucleases

28 December 2019

cites work

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High-frequency homologous recombination in plants mediated by zinc-finger nucleases

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Chimeric nucleases stimulate gene targeting in human cells

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases

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Custom zinc-finger nucleases for use in human cells

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A detailed study of the substrate specificity of a chimeric restriction enzyme.

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Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

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Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage

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Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

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Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

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Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains

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Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

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The use of zinc finger peptides to study the role of specific factor binding sites in the chromatin environment.

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Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins

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Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

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Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

31 March 2020

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Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene

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Validated zinc finger protein designs for all 16 GNN DNA triplet targets

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Human zinc fingers as building blocks in the construction of artificial transcription factors.

31 March 2020

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Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors

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Suppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels

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Artificial transcription factors increase production of recombinant antibodies in Chinese hamster ovary cells

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Toward a functional annotation of the human genome using artificial transcription factors

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Phenotypic alteration and target gene identification using combinatorial libraries of zinc finger proteins in prokaryotic cells

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Identification and use of zinc finger transcription factors that increase production of recombinant proteins in yeast and mammalian cells.

31 March 2020

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Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

31 March 2020

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Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

31 March 2020

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Design and selection of novel Cys2His2 zinc finger proteins

31 March 2020

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DNA recognition by Cys2His2 zinc finger proteins

31 March 2020

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Synergy between adjacent zinc fingers in sequence-specific DNA recognition

31 March 2020

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Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers

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Design, engineering, and characterization of zinc finger nucleases

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Activation of prokaryotic transcription through arbitrary protein-protein contacts.

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A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions

31 March 2020

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Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

31 March 2020

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31 March 2020

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Genetic reprogramming of tumor cells by zinc finger transcription factors

31 March 2020

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Drug discovery with engineered zinc-finger proteins

31 March 2020

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31 March 2020

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Custom DNA-binding proteins and artificial transcription factors

31 March 2020

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Positive and negative regulation of endogenous genes by designed transcription factors

31 March 2020

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PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

31 March 2020

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A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NPROT.2006.259

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17406455%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 December 2019

1012352868

0 references

1 reference

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