HIV-1 protease catalytic efficiency effects caused by random single amino acid substitutions (Q33262963)

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English	HIV-1 protease catalytic efficiency effects caused by random single amino acid substitutions	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

17090696

retrieved

24 July 2017

title

HIV-1 protease catalytic efficiency effects caused by random single amino acid substitutions (English)

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

author

Miguel A Martinez

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Miguel Angel Martínez

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4

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

Bonaventura Clotet Sala

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3

object named as

Bonaventura Clotet

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stated in

Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

Mariona Parera

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1

object named as

Mariona Parera

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

Guerau Fernandez

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2

object named as

Guerau Fernàndez

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

publication date

7 November 2006

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

published in

Molecular Biology and Evolution

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

volume

24

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

issue

2

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

page(s)

382-387

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Europe PubMed Central

PubMed publication ID

17090696

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24 July 2017

cites work

Identification of the minimal conserved structure of HIV-1 protease in the presence and absence of drug pressure.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting the tolerance of proteins to random amino acid substitution

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tolerance to random amino acid change

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of hormone-receptor complexity by molecular exploitation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Genetic screen for monitoring severe acute respiratory syndrome coronavirus 3C-like protease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants of the rate of protein evolution in yeast.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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A bacteriophage lambda-based genetic screen for characterization of the activity and phenotype of the human immunodeficiency virus type 1 protease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein stability promotes evolvability

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epistasis correlates to genomic complexity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

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Structural and evolutionary relationships between retroviral and eukaryotic aspartic proteinases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic screen for the isolation and characterization of site-specific proteases

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epistasis and its relationship to canalization in the RNA virus phi 6.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why are proteins so robust to site mutations?

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The evolutionary origin of complex features

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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The contribution of epistasis to the architecture of fitness in an RNA virus

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete mutagenesis of the HIV-1 protease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic mutation of bacteriophage T4 lysozyme

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retracing the evolutionary pathways of human immunodeficiency virus type 1 resistance to protease inhibitors: virus fitness in the absence and in the presence of drug

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring the functional robustness of an enzyme by in vitro evolution

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Viral quasispecies and the problem of vaccine-escape and drug-resistant mutants.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Genetic screen for monitoring hepatitis C virus NS3 serine protease activity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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The 'evolvability' of promiscuous protein functions

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folded monomer of HIV-1 protease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic efficiency and phenotype of HIV-1 proteases encoding single critical resistance substitutions

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Robustness, evolvability, and neutrality

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

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Hypermutagenic PCR involving all four transitions and a sizeable proportion of transversions.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Update of the drug resistance mutations in HIV-1: Fall 2005.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural Selection and the Concept of a Protein Space

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for Positive Epistasis in HIV-1

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of mutational robustness

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An integrated view of protein evolution

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of genetic robustness in RNA viruses

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamic prediction of protein neutrality

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17090696

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/MOLBEV/MSL168

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17090696

retrieved

24 July 2017

PMC publication ID

7107532

0 references

PubMed publication ID

17090696

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17090696

retrieved

24 July 2017

ResearchGate publication ID

6705976

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