An efficient rapid system for profiling the cellular activities of molecular libraries. (Q33234459)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16492761%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

An efficient rapid system for profiling the cellular activities of molecular libraries (English)

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17 January 2020

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17 January 2020

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17 January 2020

Peter G Schultz

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17 January 2020

Nathanael S Gray

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17 January 2020

Jonathan S Melnick

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17 January 2020

Jeff Janes

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17 January 2020

Sungjoon Kim

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17 January 2020

Jim Y Chang

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17 January 2020

Daniel G Sipes

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17 January 2020

Drew Gunderson

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17 January 2020

Laura Jarnes

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17 January 2020

Jason T Matzen

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17 January 2020

Michael E Garcia

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17 January 2020

Tami L Hood

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17 January 2020

Ronak Beigi

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17 January 2020

Gang Xia

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17 January 2020

Richard A Harig

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17 January 2020

Hayk Asatryan

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17 January 2020

Yingyao Zhou

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17 January 2020

Xiang-Ju Gu

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17 January 2020

Alham Saadat

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17 January 2020

Vicki Zhou

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17 January 2020

Frederick J King

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17 January 2020

Christopher M Shaw

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17 January 2020

Robert Downs

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17 January 2020

Markus Warmuth

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17 January 2020

Jeremy S Caldwell

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17 January 2020

language of work or name

English

0 references

publication date

21 February 2006

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

17 January 2020

published in

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17 January 2020

volume

103

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17 January 2020

issue

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17 January 2020

page(s)

3153-3158

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Loss of response to imatinib: mechanisms and management

17 January 2020

cites work

1 reference

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Chemical genetic approaches to kinase drug discovery

21 June 2018

1 reference

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Features of selective kinase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

21 June 2018

1 reference

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Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation.

21 June 2018

1 reference

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Angiopoietin/Tie2 signaling, tumor angiogenesis and inflammatory diseases

21 June 2018

1 reference

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Eph receptor tyrosine kinases in tumor and tumor microenvironment

21 June 2018

1 reference

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Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2

21 June 2018

1 reference

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Systems biology in drug discovery

21 June 2018

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Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models

21 June 2018

1 reference

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Eph receptor tyrosine kinases in angiogenesis: from development to disease.

21 June 2018

1 reference

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Overriding imatinib resistance with a novel ABL kinase inhibitor

21 June 2018

1 reference

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Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis

21 June 2018

1 reference

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Method for analyzing signaling networks in complex cellular systems

21 June 2018

1 reference

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A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo

21 June 2018

1 reference

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Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs

21 June 2018

1 reference

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Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412.

21 June 2018

1 reference

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Mechanisms and functions of Eph and ephrin signalling

21 June 2018

1 reference

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Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate

21 June 2018

1 reference

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Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

A concise and traceless linker strategy toward combinatorial libraries of 2,6,9-substituted purines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

Oncogenic kinase signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

The role of tyrosine phosphorylation in cell growth and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

A new era in the treatment of erectile dysfunction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413928

Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity

21 June 2018

1 reference

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A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 June 2018

1 reference

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Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.

21 June 2018

1 reference

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

21 June 2018

1 reference

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The novel activation of ABL by fusion to an ets-related gene, TEL.

21 June 2018

1 reference

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

21 June 2018

1 reference

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Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0511292103

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16492761

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tyrosine kinases as targets for cancer therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16492761

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0511292103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16492761%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

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17 January 2020

PubMed publication ID

16492761

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16492761%20AND%20SRC:MED&resulttype=core&format=json