Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors (Q33211908)

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English	Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 July 2017

Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

15

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24 July 2017

object named as

Hongjun Fu

4

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Paul R. Carlier

object named as

Paul R Carlier

14

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object named as

Hong Xue

13

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object named as

Yifan Han

18

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3

object named as

Hugh H N Chan

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24 July 2017

6

object named as

Hing Wai Tsang

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24 July 2017

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object named as

Jialie Luo

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24 July 2017

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object named as

Keming Xiong

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24 July 2017

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object named as

Karl W K Tsim

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24 July 2017

author name string

Wenming Li

1

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24 July 2017

Rongbiao Pi

2

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24 July 2017

Nelson T K Lee

5

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24 July 2017

Yongmei Pu

7

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24 July 2017

Donald C Chang

8

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24 July 2017

Chaoying Li

9

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24 July 2017

Zhiwang Li

12

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24 July 2017

Mingtao Li

17

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24 July 2017

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publication date

14 February 2005

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24 July 2017

Journal of Biological Chemistry

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24 July 2017

280

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24 July 2017

18

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24 July 2017

18179-18188

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PubMed publication ID

24 July 2017

Highly potent, selective, and low cost bis-tetrahydroaminacrine inhibitors of acetylcholinesterase. Steps toward novel drugs for treating Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Effects of bis(7)-tacrine, a novel anti-Alzheimer's agent, on rat brain AChE.

1 reference

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21 January 2018

Bis(7)-tacrine, a novel acetylcholinesterase inhibitor, reverses AF64A-induced deficits in navigational memory in rats.

1 reference

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21 January 2018

Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor [corrected].

1 reference

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21 January 2018

New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer's disease

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https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

The pharmacotherapy of Alzheimer's disease based on the cholinergic hypothesis: an update

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Donepezil hydrochloride (E2020) and other acetylcholinesterase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Huperzine A attenuates cognitive dysfunction and neuronal degeneration caused by beta-amyloid protein-(1-40) in rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

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21 January 2018

The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Apoptosis and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

The changing landscape of ischaemic brain injury mechanisms.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Effect of acute calcium influx after mechanical stretch injury in vitro on the viability of hippocampal neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

The p38 signal transduction pathway: activation and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Tacrine attenuates hydrogen peroxide-induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Carbachol blocks beta-amyloid fragment 31-35-induced apoptosis in cultured cortical neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system

1 reference

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21 January 2018

Acetylcholinesterase--new roles for an old actor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Induction of acetylcholinesterase expression during apoptosis in various cell types

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Toxic effects of acetylcholinesterase on neuronal and glial-like cells in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Increased expression of intranuclear AChE involved in apoptosis of SK-N-SH cells

1 reference

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21 January 2018

Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Excitatory amino acid receptors, second messengers and regulation of intracellular Ca2+ in mammalian neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

Pharmacotherapeutic approaches to the treatment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411085200

21 January 2018

What are the treatment options for patients with severe Alzheimer's disease?

1 reference

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21 January 2018

Do acetylcholinesterase inhibitors boost synaptic scaling in Alzheimer's disease?

1 reference

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21 January 2018

Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M411085200

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

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