Identification of an inhibitor-binding site to HIV-1 integrase with affinity acetylation and mass spectrometry (Q33202469)

23 July 2017

title

Identification of an inhibitor-binding site to HIV-1 integrase with affinity acetylation and mass spectrometry (English)

1 reference

23 July 2017

Mamuka Kvaratskhelia

1 reference

23 July 2017

Sonja Hess

1 reference

23 July 2017

Nick Shkriabai

1 reference

23 July 2017

Sachindra S Patil

1 reference

23 July 2017

Scott R Budihas

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23 July 2017

Robert Craigie

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23 July 2017

Terrence R Burke

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23 July 2017

Stuart F J Le Grice

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23 July 2017

language of work or name

English

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publication date

26 April 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

23 July 2017

published in

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23 July 2017

volume

101

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23 July 2017

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23 July 2017

page(s)

6894-6899

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Reversion of the lethal phenotype of an HIV-1 integrase mutant virus by overexpression of the same integrase mutant protein.

23 July 2017

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Human immunodeficiency virus type-1 integrase containing a glycine to serine mutation at position 140 is attenuated for catalysis and resistant to integrase inhibitors

21 June 2018

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Human immunodeficiency virus type 1 nucleocapsid zn(2+) fingers are required for efficient reverse transcription, initial integration processes, and protection of newly synthesized viral DNA.

21 June 2018

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21 June 2018

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Mapping the epitope of an inhibitory monoclonal antibody to the C-terminal DNA-binding domain of HIV-1 integrase.

21 June 2018

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Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

21 June 2018

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Arylisothiocyanate-containing esters of caffeic acid designed as affinity ligands for HIV-1 integrase

21 June 2018

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Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain

21 June 2018

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HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

21 June 2018

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21 June 2018

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Retroviral integrase inhibitors year 2000: update and perspectives

21 June 2018

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Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters

21 June 2018

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Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

21 June 2018

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 June 2018

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Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

21 June 2018

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Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: stimulation by the viral nucleocapsid protein

21 June 2018

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Chicoric acid analogues as HIV-1 integrase inhibitors

21 June 2018

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The barrier-to-autointegration protein is a host factor for HIV type 1 integration

21 June 2018

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Resistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integrase

21 June 2018

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Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

21 June 2018

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A previously unidentified host protein protects retroviral DNA from autointegration

21 June 2018

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Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

21 June 2018

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Human immunodeficiency virus type 1 nucleocapsid protein specifically stimulates Mg2+-dependent DNA integration in vitro

21 June 2018

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HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching

21 June 2018

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HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro

21 June 2018

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Nucleotide binding by the HIV-1 integrase protein in vitro.

21 June 2018

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21 June 2018

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Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

21 June 2018

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21 June 2018

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Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

21 June 2018

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Solution structure of the DNA binding domain of HIV-1 integrase

21 June 2018

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The DNA-binding domain of HIV-1 integrase has an SH3-like fold

21 June 2018

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Interfacial peptide inhibitors of HIV-1 integrase activity and dimerization

21 June 2018

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21 January 2018

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New developments in anti-HIV chemotherapy

31 October 2018

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A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

21 January 2018

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Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

21 January 2018

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Peptide inhibitors of HIV-1 integrase dissociate the enzyme oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400873101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0400873101

1 reference

23 July 2017

0 references

1 reference

23 July 2017

1 reference