A role for fMRI in optimizing CNS drug development (Q31036354)

28 June 2017

title

A role for fMRI in optimizing CNS drug development (English)

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functional magnetic resonance imaging

28 June 2017

main subject

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David Borsook

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28 June 2017

Lino Becerra

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28 June 2017

Richard Hargreaves

series ordinal

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28 June 2017

publication date

1 May 2006

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Nature Reviews Drug Discovery

28 June 2017

published in

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28 June 2017

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28 June 2017

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28 June 2017

page(s)

411-424

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Can the pharmaceutical industry reduce attrition rates?

28 June 2017

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21 January 2018

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Functional imaging of pain and analgesia--a valid diagnostic tool?

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Human brain activation under controlled thermal stimulation and habituation to noxious heat: an fMRI study

21 January 2018

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21 January 2018

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A fMRI study of brain activations during non-noxious and noxious electrical stimulation of the sciatic nerve of rats

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Differential coding of hyperalgesia in the human brain: a functional MRI study

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A role for the brainstem in central sensitisation in humans. Evidence from functional magnetic resonance imaging

21 January 2018

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Pain catastrophizing and neural responses to pain among persons with fibromyalgia

21 January 2018

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Dissociable brain activation responses to 5-Hz electrical pain stimulation: a high-field functional magnetic resonance imaging study

21 January 2018

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Somatotopic organisation of the human insula to painful heat studied with high resolution functional imaging.

21 January 2018

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Painful stimuli evoke different stimulus-response functions in the amygdala, prefrontal, insula and somatosensory cortex: a single-trial fMRI study

21 January 2018

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Differentiating cortical areas related to pain perception from stimulus identification: temporal analysis of fMRI activity

21 January 2018

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Functional MRI study of thalamic and cortical activations evoked by cutaneous heat, cold, and tactile stimuli

21 January 2018

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Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study

21 January 2018

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Visceral and cutaneous pain representation in parasylvian cortex.

21 January 2018

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Cortical processing of visceral and somatic stimulation: differentiating pain intensity from unpleasantness.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Effects of D2 dopamine receptor agonist and antagonist on brain activity in the rat assessed by functional magnetic resonance imaging

21 January 2018

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Mapping the effects of the selective dopamine D2/D3 receptor agonist quinelorane using pharmacological magnetic resonance imaging

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Imaging localised dynamic changes in the nucleus accumbens following nicotine withdrawal in rats

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An fMRI study of cortical representation of mechanical allodynia in patients with neuropathic pain

21 January 2018

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A path to improved pharmaceutical productivity

21 January 2018

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Somatotopic activation in the human trigeminal pain pathway.

31 March 2020

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Reorganization of cerebral circuits in human brain lesion.

31 March 2020

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Visual areas in macaque cortex measured using functional magnetic resonance imaging.

31 March 2020

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Nerve growth factor alleviates a painful peripheral neuropathy in rats

31 March 2020

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Efficacy and safety of recombinant human nerve growth factor in patients with diabetic polyneuropathy: A randomized controlled trial. rhNGF Clinical Investigator Group

31 March 2020

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Aprepitant: an oral NK1 antagonist for the prevention of nausea and vomiting induced by highly emetogenic chemotherapy.

31 March 2020

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The economics of follow-on drug research and development: trends in entry rates and the timing of development

31 March 2020

1 reference

fMRI measurement of CNS responses to naloxone infusion and subsequent mild noxious thermal stimuli in healthy volunteers

31 March 2020

1 reference

The hippocampus in schizophrenia

31 March 2020

1 reference

Genetic basis for individual variations in pain perception and the development of a chronic pain condition

31 March 2020

1 reference

Specific and somatotopic functional magnetic resonance imaging activation in the trigeminal ganglion by brush and noxious heat

31 March 2020

1 reference

Functional magnetic resonance imaging in rats subjected to intense electrical and noxious chemical stimulation of the forepaw

31 March 2020

1 reference

Evidence of augmented central pain processing in idiopathic chronic low back pain

31 March 2020

1 reference

Regional intensive and temporal patterns of functional MRI activation distinguishing noxious and innocuous contact heat.

31 March 2020

1 reference

Heroin-induced neuronal activation in rat brain assessed by functional MRI

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD2027

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Dimensions Publication ID

28 June 2017

1048829406

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