The genetics of aging-- implications for pharmacogenomics (Q30841244)

27 June 2017

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title

The genetics of aging-- implications for pharmacogenomics (English)

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27 June 2017

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27 June 2017

Annibale Puca

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27 June 2017

language of work or name

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1 July 2002

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27 June 2017

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27 June 2017

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27 June 2017

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27 June 2017

page(s)

469-484

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The end of world population growth

27 June 2017

cites work

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https://api.crossref.org/works/10.1517%2F14622416.3.4.469

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Longevity is moderately heritable in a sample of Danish twins born 1870-1880.

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Evolution of human longevity and the genetic complexity governing aging rate

21 January 2018

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Slowing of mortality rates at older ages in large medfly cohorts

21 January 2018

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Identifying families with likely genetic protective factors against Alzheimer disease

21 January 2018

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Genetic associations with human longevity at the APOE and ACE loci

21 January 2018

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Reduced apolipoprotein epsilon 4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals.

21 January 2018

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Regional patterns of disability-free life expectancy and disability-adjusted life expectancy: global Burden of Disease Study

21 January 2018

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Aging, health risks, and cumulative disability

21 January 2018

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Thyroid and other organ-specific autoantibodies in healthy centenarians

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The immunology of exceptional individuals: the lesson of centenarians.

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Gene polymorphisms predicting high plasma levels of coagulation and fibrinolysis proteins. A study in centenarians.

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Mental Aging and Its Medico-Psycho-Social Background in the Very Old Japanese

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Life-long sustained mortality advantage of siblings of centenarians

21 January 2018

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Genetic dissection of complex traits

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Familial excess longevity in Utah genealogies.

21 January 2018

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Inheritance of human longevity in Iceland.

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21 January 2018

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The evolution of menopause and human life span

21 January 2018

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Evolution of senescence: late survival sacrificed for reproduction

21 January 2018

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p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

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Positional cloning of the Werner's syndrome gene

21 January 2018

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The Werner syndrome protein is a DNA helicase

21 January 2018

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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Molecular mechanisms of yeast longevity

21 January 2018

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Aging and resistance to oxidative damage in Caenorhabditis elegans

21 January 2018

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

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Determination of life-span in Caenorhabditis elegans by four clock genes

21 January 2018

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Signals from the reproductive system regulate the lifespan of C. elegans

21 January 2018

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A C. elegans mutant that lives twice as long as wild type

21 January 2018

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Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

21 January 2018

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Extended life-span and stress resistance in the Drosophila mutant methuselah

21 January 2018

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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

21 January 2018

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Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

21 January 2018

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Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice

21 January 2018

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A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants

21 January 2018

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

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FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies

21 January 2018

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Causes, effects, and constraints in the genetics of human longevity

21 January 2018

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Gene expression profile of aging and its retardation by caloric restriction

21 January 2018

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A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4.

21 January 2018

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Telomere length, aging, and somatic cell turnover

21 January 2018

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Structure and function of telomeres

21 January 2018

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Telomeres shorten during ageing of human fibroblasts

21 January 2018

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Telomere reduction in human colorectal carcinoma and with ageing

21 January 2018

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The rate of telomere sequence loss in human leukocytes varies with age.

21 January 2018

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Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

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Telomere length regulation

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.4.469

Middle-aged mothers live longer

21 January 2018

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Human longevity at the cost of reproductive success

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.4.469

Centenarians: the older you get, the healthier you have been

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.3.4.469

Siblings of centenarians live longer

21 January 2018

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https://api.crossref.org/works/10.1517%2F14622416.3.4.469

Validity of reported age and centenarian prevalence in New England

21 January 2018

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21 January 2018

Identifiers

DOI

10.1517/14622416.3.4.469

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27 June 2017

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