A combinatorial approach to hybrid enzymes independent of DNA homology (Q30823110)

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English	A combinatorial approach to hybrid enzymes independent of DNA homology	scientific article

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

title

A combinatorial approach to hybrid enzymes independent of DNA homology (English)

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

author name string

Ostermeier M

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1

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

Shim JH

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2

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

Benkovic SJ

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3

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

publication date

1 December 1999

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

published in

Nature Biotechnology

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

volume

17

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

issue

12

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

page(s)

1205-1209

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Europe PubMed Central

PubMed publication ID

10585719

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26 June 2017

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Random-priming in vitro recombination: An effective tool for directed evolution

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Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

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Rapid evolution of a protein in vitro by DNA shuffling

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Antibody scFv fragments without disulfide bonds made by molecular evolution

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Directed evolution of a thermostable esterase.

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Directed evolution converts subtilisin E into a functional equivalent of thermitase

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Improved green fluorescent protein by molecular evolution using DNA shuffling

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Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening

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A hierarchical approach to protein molecular evolution

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Combinatorial protein engineering by incremental truncation

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Incremental truncation as a strategy in the engineering of novel biocatalysts

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Synchronous digestion of SV40 DNA by exonuclease III.

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De novo purine nucleotide biosynthesis: cloning of human and avian cDNAs encoding the trifunctional glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase by functional complementatio

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The human glycinamide ribonucleotide transformylase domain: purification, characterization, and kinetic mechanism

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Heterologous expression and purification of active human phosphoribosylglycinamide formyltransferase as a single domain

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Protein Structure-Based Design, Synthesis, and Biological Evaluation of 5-Thia-2,6-diamino-4(3H)-oxopyrimidines: Potent Inhibitors of Glycinamide Ribonucleotide Transformylase with Potent Cell Growth Inhibition

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The Protein Data Bank: a computer-based archival file for macromolecular structures

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

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Pentapeptide scanning mutagenesis: random insertion of a variable five amino acid cassette in a target protein

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Mapping catalytically important regions of an enzyme using two-codon insertion mutagenesis: a case study correlating beta-lactamase mutants with the three-dimensional structure

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Creating a bifunctional protein by insertion of β-lactamase into the maltodextrin-binding protein

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Random insertion of GFP into the cAMP-dependent protein kinase regulatory subunit from Dictyostelium discoideum

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A rapid screen of active site mutants in glycinamide ribonucleotide transformylase.

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Structures of apo and complexed Escherichia coli glycinamide ribonucleotide transformylase

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New enzyme lineages by subdomain shuffling

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Assembly of an active enzyme by the linkage of two protein modules

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Hybrid enzymes: manipulating enzyme design

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Optimization of DNA shuffling for high fidelity recombination

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Evaluation of the kinetic mechanism of Escherichia coli glycinamide ribonucleotide transformylase

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7 January 2021

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Identifiers

DOI

10.1038/70754

1 reference

stated in

Europe PubMed Central

PubMed publication ID

10585719

retrieved

26 June 2017

PubMed publication ID

10585719

1 reference

stated in

Europe PubMed Central

PubMed publication ID

10585719

retrieved

26 June 2017

ResearchGate publication ID

12715036

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