Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells (Q30824578)

1 October 2017

Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells (English)

1 reference

1 October 2017

1 reference

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2 June 2020

1 reference

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2 June 2020

Mario A Cepeda

1 reference

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2 June 2020

Jacob J H Pelling

1 reference

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2 June 2020

Caitlin L Evered

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Karla C Williams

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Zoey Freedman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ioana Stan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Jessica A Willson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

1 reference

18 October 2016

1 reference

1 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

1 reference

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2 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

1 reference

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describes a project that uses

2 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5070195/fullTextXML

inferred from PubMed Central ID database lookup

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ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth

21 June 2018

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Quantitative measurement of invadopodia-mediated extracellular matrix proteolysis in single and multicellular contexts

21 June 2018

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Analysis of the MMP-dependent and independent functions of tissue inhibitor of metalloproteinase-2 on the invasiveness of breast cancer cells.

21 June 2018

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Phosphorylation of membrane type 1-matrix metalloproteinase (MT1-MMP) and its vesicle-associated membrane protein 7 (VAMP7)-dependent trafficking facilitate cell invasion and migration

21 June 2018

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21 June 2018

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Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors

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21 June 2018

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Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells

21 June 2018

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Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

21 June 2018

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Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy

21 June 2018

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Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells

21 June 2018

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Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential.

21 June 2018

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21 June 2018

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Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells.

21 June 2018

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Breaching the basement membrane: who, when and how?

21 June 2018

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Unraveling the microenvironmental influences on the normal mammary gland and breast cancer

21 June 2018

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A human breast cell model of preinvasive to invasive transition.

21 June 2018

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Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene

21 June 2018

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The tumor microenvironment: regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2.

21 June 2018

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Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism

21 June 2018

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 June 2018

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New signals from the invasive front

21 June 2018

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Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function

21 June 2018

1 reference

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Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation

21 June 2018

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21 June 2018

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TIMP-2: an endogenous inhibitor of angiogenesis

21 June 2018

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Matrix metalloproteinase inhibitors (MMPIs): the beginning of phase I or the termination of phase III clinical trials

21 June 2018

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Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

21 June 2018

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Membrane type-1 matrix metalloproteinase and TIMP-2 in tumor angiogenesis.

21 June 2018

1 reference

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Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion

21 June 2018

1 reference

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Dissemination and growth of cancer cells in metastatic sites

21 June 2018

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CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain.

21 June 2018

1 reference

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Marimastat as maintenance therapy for patients with advanced gastric cancer: a randomised trial

21 June 2018

1 reference

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New functions for the matrix metalloproteinases in cancer progression

21 June 2018

1 reference

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 June 2018

1 reference

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Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5070195

Metalloproteinases: role in breast carcinogenesis, invasion and metastasis

21 June 2018

1 reference

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Changing views of the role of matrix metalloproteinases in metastasis

21 June 2018

1 reference

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Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases

21 June 2018

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Tumor progression in four mammary epithelial cell lines derived from the same patient

21 June 2018

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Tumor Cell Invasion Inhibited by TIMP-2

21 June 2018

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Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in brea

21 June 2018

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Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP).

21 January 2018

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Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence

21 January 2018

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High levels of TIMP-2 correlate with adverse prognosis in breast cancer.

21 January 2018

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Reproducibility: Standardize antibodies used in research.

21 January 2018

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High levels of messenger RNAs for tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in primary breast carcinomas are associated with development of distant metastases

21 January 2018

1 reference

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Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro

25 November 2018

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12 December 2020

Activation of the extracellular signal-regulated protein kinase (ERK) cascade by membrane-type-1 matrix metalloproteinase (MT1-MMP)

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12 December 2020

Type IV collagen induces matrix metalloproteinase 2 activation in HT1080 fibrosarcoma cells

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12 December 2020

High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma

1 reference

12 December 2020

MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization

1 reference

12 December 2020

Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes

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12 December 2020

Biophysical and functional characterization of full-length, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli. Comparison of wild type and amino-terminal alanine appended variant with implications for t

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12 December 2020

In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer

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12 December 2020

MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease

1 reference

12 December 2020

10.1186/S12943-016-0547-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

27756325

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27756325%20AND%20SRC:MED&resulttype=core&format=json