Molecular analysis of the EGFR-RAS-RAF pathway in pancreatic ductal adenocarcinomas: lack of mutations in the BRAF and EGFR genes (Q30811836)

26 June 2017

title

Molecular analysis of the EGFR-RAS-RAF pathway in pancreatic ductal adenocarcinomas: lack of mutations in the BRAF and EGFR genes (English)

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26 June 2017

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Anders Molven

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26 June 2017

Heike Immervoll

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26 June 2017

Dag Hoem

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26 June 2017

Kalaiarasy Kugarajh

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26 June 2017

Solrun J Steine

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26 June 2017

publication date

6 April 2006

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26 June 2017

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26 June 2017

volume

448

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26 June 2017

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26 June 2017

page(s)

788-796

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BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets

26 June 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00428-006-0191-8

Sensitive sequencing method for KRAS mutation detection by Pyrosequencing

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00428-006-0191-8

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00428-006-0191-8

Detection of point mutation in K-ras oncogene at codon 12 in pancreatic diseases

21 January 2018

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12 December 2020

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

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12 December 2020

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

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12 December 2020

Long-term results of partial pancreaticoduodenectomy for ductal adenocarcinoma of the pancreatic head: 25-year experience

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12 December 2020

Orthotopic transplantation models of pancreatic adenocarcinoma derived from cell lines and primary tumors and displaying varying metastatic activity

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12 December 2020

Method of mutation analysis may contribute to discrepancies in reports of (V599E)BRAF mutation frequencies in melanocytic neoplasms

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12 December 2020

Mutational activation of the RAS-RAF-MAPK and the Wnt pathway in small intestinal adenocarcinomas

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12 December 2020

BRAF mutations in papillary carcinomas of the thyroid

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12 December 2020

Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation

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12 December 2020

Mutations of the BRAF gene in human cancer

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12 December 2020

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization

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12 December 2020

Cancer statistics, 2003.

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12 December 2020

Inherited predisposition to cancer: a historical overview.

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12 December 2020

Somatic alterations in the human cancer genome

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12 December 2020

BRAF and K-ras gene mutations in human pancreatic cancers.

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12 December 2020

Comparison of K-ras point mutations at codon 12 and p21 expression in pancreatic cancer between Japanese and Chinese patients.

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12 December 2020

K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma

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12 December 2020

BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas.

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12 December 2020

Epidemiology and prevention of pancreatic cancer

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12 December 2020

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12 December 2020

Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma

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12 December 2020

Mutations of BRAF and KRAS2 in the development of Barrett's adenocarcinoma

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12 December 2020

BRAF and NRAS Mutations Are Frequent in Nodular Melanoma but Are not Associated with Tumor Cell Proliferation or Patient Survival

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12 December 2020

Familial pancreatic cancer

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12 December 2020

Progression model for pancreatic cancer.

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12 December 2020

Defective DNA mismatch repair in long-term (> or =3 years) survivors with pancreatic cancer

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12 December 2020

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

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12 December 2020

RAF/RAS oncogenes and mismatch-repair status

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12 December 2020

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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12 December 2020

Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysis

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12 December 2020

The K-ras mutation pattern in pancreatic ductal adenocarcinoma usually is identical to that in associated normal, hyperplastic, and metaplastic ductal epithelium.

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12 December 2020

Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+

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12 December 2020

High frequency of mutations of the PIK3CA gene in human cancers

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12 December 2020

Tumor-suppressive pathways in pancreatic carcinoma.

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12 December 2020

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

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12 December 2020

Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation

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12 December 2020

Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability

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12 December 2020

Does anyone survive pancreatic ductal adenocarcinoma? A nationwide study re-evaluating the data of the Finnish Cancer Registry

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12 December 2020

Mutational analysis of BRAF in gallbladder carcinomas in association with K-ras and p53 mutations and microsatellite instability.

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12 December 2020

Tracing origin of serrated adenomas with BRAF and KRAS mutations.

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12 December 2020

A Two-Step Enriched-Nested PCR Technique Enhances Sensitivity for Detection of Codon 12 K-ras Mutations in Pancreatic Adenocarcinoma

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12 December 2020

Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha

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12 December 2020

Ki-ras and p53 gene mutations in pancreatic ductal carcinoma: a relationship with tumor phenotype and survival

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12 December 2020

10.1007/S00428-006-0191-8

Identifiers

DOI

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26 June 2017

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