Contributions of CDR3 to V H H domain stability and the design of monobody scaffolds for naive antibody libraries (Q30788281)

26 June 2017

title

Contributions of CDR3 to V H H domain stability and the design of monobody scaffolds for naive antibody libraries (English)

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26 June 2017

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Christopher J Bond

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26 June 2017

James C Marsters

series ordinal

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26 June 2017

Sachdev S Sidhu

series ordinal

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26 June 2017

language of work or name

English

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publication date

1 September 2003

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Journal of Molecular Biology

26 June 2017

published in

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26 June 2017

volume

332

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26 June 2017

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26 June 2017

page(s)

643-655

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Naturally occurring antibodies devoid of light chains

26 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Biophysical Properties of Camelid VHHDomains Compared to Those of Human VH3 Domains†

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Redefining the minimal antigen-binding fragment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Length distribution of CDRH3 in antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Novel frameworks as a source of high-affinity ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Phage display of combinatorial antibody libraries.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Phage display in pharmaceutical biotechnology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

By-passing immunization. Human antibodies from V-gene libraries displayed on phage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Construction of a semisynthetic antibody library using trinucleotide oligos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Selection of an anti-IGF-1 Fab from a Fab phage library created by mutagenesis of multiple CDR loops

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Antibody arrays for high-throughput screening of antibody-antigen interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

The crystal structure of a llama heavy chain variable domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Biophysical properties of human antibody variable domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Lateral recognition of a dye hapten by a llama VHH domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Camelid heavy-chain variable domains provide efficient combining sites to haptens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Selection by phage display of llama conventional V(H) fragments with heavy chain antibody V(H)H properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Solution structure of a llama single-domain antibody with hydrophobic residues typical of the VH/VL interface

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Staphylococcal protein A binding to VH3 encoded immunoglobulins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

High copy display of large proteins on phage for functional selections

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Llama heavy-chain V regions consist of at least four distinct subfamilies revealing novel sequence features

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Rapid mapping of protein functional epitopes by combinatorial alanine scanning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the Erbin PDZ domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

A minimized M13 coat protein defines the requirements for assembly into the bacteriophage particle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Quantifying beta-sheet stability by phage display

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Complementarity-determining region 2 is implicated in the binding of staphylococcal protein A to human immunoglobulin VHIII variable regions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Identification of specificity-determining residues in antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Structural repertoire of the human VH segments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Conformations of the third hypervariable region in the VH domain of immunoglobulins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Reshaping human antibodies: grafting an antilysozyme activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Mapping and modification of an antibody hapten binding site: a site-directed mutagenesis study of McPC603.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

"ATG vectors' for regulated high-level expression of cloned genes in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Rapid and efficient site-specific mutagenesis without phenotypic selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

Phage display for selection of novel binding peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900967-7

10.1016/S0022-2836(03)00967-7

7 January 2021

Identifiers

DOI

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26 June 2017

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