Efficacy and safety of laquinimod in multiple sclerosis: current status (Q30694702)

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29 February 2020

title

Efficacy and safety of laquinimod in multiple sclerosis: current status (English)

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29 February 2020

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29 February 2020

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29 February 2020

Shalom Haggiag

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29 February 2020

publication date

1 November 2013

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Therapeutic advances in neurological disorders

29 February 2020

published in

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29 February 2020

volume

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issue

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page(s)

343-352

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Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis.

29 February 2020

cites work

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Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination

20 June 2018

1 reference

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Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity

20 June 2018

1 reference

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Placebo-controlled trial of oral laquinimod for multiple sclerosis

20 June 2018

1 reference

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Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study.

20 June 2018

1 reference

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Cost of multiple sclerosis by level of disability: a review of literature.

20 June 2018

1 reference

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Treatment with laquinimod reduces development of active MRI lesions in relapsing MS.

20 June 2018

1 reference

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Laquinimod prevents inflammation-induced synaptic alterations occurring in experimental autoimmune encephalomyelitis

20 June 2018

1 reference

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Oral treatment with laquinimod augments regulatory T-cells and brain-derived neurotrophic factor expression and reduces injury in the CNS of mice with experimental autoimmune encephalomyelitis

11 August 2018

1 reference

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Modulation of autoimmune demyelination by laquinimod via induction of brain-derived neurotrophic factor

11 August 2018

1 reference

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Oral laquinimod in patients with relapsing-remitting multiple sclerosis: 36-week double-blind active extension of the multi-centre, randomized, double-blind, parallel-group placebo-controlled study

11 August 2018

1 reference

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Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825117

Laquinimod suppress antigen presentation in relapsing-remitting multiple sclerosis: in-vitro high-throughput gene expression study

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825117

Laquinimod (ABR-215062) suppresses the development of experimental autoimmune encephalomyelitis, modulates the Th1/Th2 balance and induces the Th3 cytokine TGF-beta in Lewis rats

11 August 2018

1 reference

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Synthesis and biological evaluation of new 1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for treatment of autoimmune disorders: structure-activity relationship

11 August 2018

1 reference

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The new orally active immunoregulator laquinimod (ABR-215062) effectively inhibits development and relapses of experimental autoimmune encephalomyelitis

11 August 2018

1 reference

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Suppression of experimental autoimmune neuritis by ABR-215062 is associated with altered Th1/Th2 balance and inhibited migration of inflammatory cells into the peripheral nerve tissue

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825117

Linomide suppresses chronic-relapsing experimental autoimmune encephalomyelitis in DA rats

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825117

Linomide suppresses acute experimental autoimmune encephalomyelitis in Lewis rats by counter-acting the imbalance of pro-inflammatory versus anti-inflammatory cytokines

11 August 2018

1 reference

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Linomide in relapsing and secondary progressive MS: part II: MRI results. MRI Analysis Center of the University of Texas-Houston, Health Science Center, and the North American Linomide Investigators

11 August 2018

1 reference

12 December 2020

Laquinimod modulates B cells and their regulatory effects on T cells in multiple sclerosis

1 reference

12 December 2020

Linomide in relapsing and secondary progressive MS: part I: trial design and clinical results. North American Linomide Investigators

1 reference

12 December 2020

Treatment of secondary progressive multiple sclerosis with the immunomodulator linomide: a double-blind, placebo-controlled pilot study with monthly magnetic resonance imaging evaluation

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12 December 2020

Identifiers

DOI

10.1177/1756285613499424

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29 February 2020

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29 February 2020

PubMed publication ID

24228070

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24228070%20AND%20SRC:MED&resulttype=core&format=json