Computational method to reduce the search space for directed protein evolution (Q30660873)

5 September 2017

Computational method to reduce the search space for directed protein evolution (English)

1 reference

5 September 2017

0 references

computational biology

1 reference

Wang ZG

1 reference

5 September 2017

Voigt CA

1 reference

5 September 2017

Mayo SL

series ordinal

1 reference

5 September 2017

Arnold FH

series ordinal

1 reference

5 September 2017

language of work or name

English

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publication date

1 March 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 September 2017

1 reference

5 September 2017

1 reference

5 September 2017

1 reference

5 September 2017

3778-3783

1 reference

Directed evolution study of temperature adaptation in a psychrophilic enzyme

5 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Exploring nonnatural evolutionary pathways by saturation mutagenesis: rapid improvement of protein function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Computational protein design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Directed evolution converts subtilisin E into a functional equivalent of thermitase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 A resolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Directed evolution of a thermostable esterase.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Design, structure and stability of a hyperthermophilic protein variant

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

DNA shuffling of a family of genes from diverse species accelerates directed evolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Creating novel enzymes by applied molecular evolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

De Novo Protein Design: Fully Automated Sequence Selection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Probing the role of packing specificity in protein design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Automated design of the surface positions of protein helices

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Subtilases: the superfamily of subtilisin-like serine proteases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

MOLMOL: a program for display and analysis of macromolecular structures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Protein design automation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Mean-field minimization methods for biological macromolecules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Backbone-dependent rotamer library for proteins. Application to side-chain prediction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Application of a self-consistent mean field theory to predict protein side-chains conformation and estimate their conformational entropy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Rapid evolution of a protein in vitro by DNA shuffling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

A relationship between protein stability and protein function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Conformational analysis of the backbone-dependent rotamer preferences of protein sidechains

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Impact of local and non-local interactions on thermodynamics and kinetics of protein folding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Development of an in vivo method to identify mutants of phage T4 lysozyme of enhanced thermostability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

The interpretation of protein structures: Estimation of static accessibility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Natural Selection and the Concept of a Protein Space

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Structural studies of mutants of T4 lysozyme that alter hydrophobic stabilization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Additivity of mutational effects in proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Predicting protein mutant energetics by self-consistent ensemble optimization

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.051614498

Emergence of Preferred Structures in a Simple Model of Protein Folding

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.051614498

Nonadditivity of mutational effects on the properties of catalase I and its application to efficient directed evolution

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31129

Continuity in evolution: on the nature of transitions

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11274394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proteins with selected sequences fold into unique native conformation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11274394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.051614498

1 reference

5 September 2017

0 references

1 reference

5 September 2017

PubMed publication ID

11274394

1 reference