Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist (Q30573156)

21 August 2017

Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist (English)

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21 August 2017

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PubMed publication ID

25 June 2017

Shohei Koyama

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Cevayir Coban

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Yoichiro Iwakura

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Shizuo Akira

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21 August 2017

Kouji Kobiyama

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21 August 2017

Taiki Aoshi

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21 August 2017

Hirotaka Narita

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21 August 2017

Etsushi Kuroda

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21 August 2017

Masayuki Hayashi

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21 August 2017

Kohhei Tetsutani

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21 August 2017

Shinichi Mochizuki

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21 August 2017

Kazuo Sakurai

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21 August 2017

Yuko Katakai

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21 August 2017

Yasuhiro Yasutomi

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21 August 2017

Shinobu Saijo

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21 August 2017

language of work or name

English

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publication date

10 February 2014

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Proceedings of the National Academy of Sciences of the United States of America

21 August 2017

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21 August 2017

111

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21 August 2017

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21 August 2017

3086-3091

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21 August 2017

Lymph node macrophages

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

CD169+ macrophages at the crossroads of antigen presentation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

CpG DNA as a vaccine adjuvant.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

A novel class of immune-stimulatory CpG oligodeoxynucleotides unifies high potency in type I interferon induction with preferred structural properties

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Visualizing B cell capture of cognate antigen from follicular dendritic cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

The cellular niche of Listeria monocytogenes infection changes rapidly in the spleen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: structural studies and immunomodulatory activity in primates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Therapeutic potential of Toll-like receptor 9 activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Immunotherapeutic uses of CpG oligodeoxynucleotides

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Structural studies of oligonucleotides containing G-quadruplex motifs using AFM.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

A Toll-like receptor recognizes bacterial DNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Mechanism and function of a newly identified CpG DNA motif in human primary B cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

CpG Oligodeoxynucleotides Act as Adjuvants that Switch on T Helper 1 (Th1) Immunity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939924

Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Polysaccharide--polynucleotide complexes. 2. Complementary polynucleotide mimic behavior of the natural polysaccharide schizophyllan in the macromolecular complex with single-stranded RNA and DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

A Polysaccharide Carrier to Effectively Deliver Native Phosphodiester CpG DNA to Antigen-Presenting Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Rod-like architecture and helicity of the poly(C)/schizophyllan complex observed by AFM and SEM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Dectin-1 stimulation induces suppressor of cytokine signaling 1, thereby modulating TLR signaling and T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Bacterial entry to the splenic white pulp initiates antigen presentation to CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1319268111

Clinical evaluation of schizophyllan combined with irradiation in patients with cervical cancer. A randomized controlled study

21 January 2018

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12 December 2020

Spontaneous Formation of Nucleic Acid-based Nanoparticles Is Responsible for High Interferon-α Induction by CpG-A in Plasmacytoid Dendritic Cells

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12 December 2020

Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide

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12 December 2020

Enhanced Cytokine Secretion from Primary Macrophages due to Dectin-1 Mediated Uptake of CpG DNA/β-1,3-Glucan Complex

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12 December 2020

Phase separation in the mixture of schizophyllan and poly(ethylene oxide) in aqueous solution driven by a specific interaction between the glucose side chain and poly(ethylene oxide)

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1319268111

1 reference

21 August 2017

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21 August 2017

PubMed publication ID

24516163

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