Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic (Q30525658)

13 August 2017

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic (English)

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13 August 2017

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Diana F Silva

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Luísa Cortes

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Manuela Grazina

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Sandra M Cardoso

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Catarina R Oliveira

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Russell H Swerdlow

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13 August 2017

Daniela M Arduíno

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13 August 2017

A Raquel Esteves

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13 August 2017

Bindi Patel

series ordinal

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13 August 2017

27 July 2012

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13 August 2017

Human Molecular Genetics

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13 August 2017

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13 August 2017

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13 August 2017

4680-4702

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describes a project that uses

13 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3471400/fullTextXML

inferred from PubMed Central ID database lookup

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Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.

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Mitochondrial metabolism modulation: a new therapeutic approach for Parkinson's disease

14 July 2018

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Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer

14 July 2018

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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

14 July 2018

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Dysfunctional mitochondria uphold calpain activation: contribution to Parkinson's disease pathology

14 July 2018

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ER-mediated stress induces mitochondrial-dependent caspases activation in NT2 neuron-like cells

14 July 2018

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Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy

14 July 2018

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Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

14 July 2018

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Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease

14 July 2018

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Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

14 July 2018

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Live-cell imaging of autophagy induction and autophagosome-lysosome fusion in primary cultured neurons

14 July 2018

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Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease

14 July 2018

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Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

14 July 2018

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Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background.

14 July 2018

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Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes

14 July 2018

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The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes

14 July 2018

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Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

14 July 2018

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Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

14 July 2018

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Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

14 July 2018

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

14 July 2018

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Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

14 July 2018

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A guided tour into subcellular colocalization analysis in light microscopy

14 July 2018

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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

14 July 2018

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

14 July 2018

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

14 July 2018

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Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth.

14 July 2018

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Role for Rab7 in maturation of late autophagic vacuoles

14 July 2018

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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation

14 July 2018

1 reference

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Apoptotic molecules and MPTP-induced cell death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Identification of functional dopamine receptors in human teratocarcinoma NT2 cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

As you like it, Part 3: A critique and historical review of calcification as seen with the electron microscope

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Experimental models of Parkinson's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Disrupted mitochondrial electron transport function increases expression of anti-apoptotic bcl-2 and bcl-X(L) proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Surface oxidase and oxidative stress propagation in aging

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Cybrids in Alzheimer's disease: a cellular model of the disease?

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Origin and functional consequences of the complex I defect in Parkinson's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Neuropathology of Parkinson's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Up-regulation of the plasma membrane oxidoreductase as a prerequisite for the viability of human Namalwa rho 0 cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Energy dependence of autophagic protein degradation in isolated rat hepatocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Effect of lysosomotropic amines on the secretory pathway and on the recycling of the asialoglycoprotein receptor in human hepatoma cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Energy dependence of different steps in the autophagic-lysosomal pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids

14 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

Mitochondrial network complexity and pathological decrease in complex I activity are tightly correlated in isolated human complex I deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

In search of an "autophagomometer".

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

Introduction. Autophagy dysregulation in neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS309

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Functional mitochondria are required for amyloid beta-mediated neurotoxicity

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471400

Energy depletion and autophagy. Cytochemical and biochemical studies in isolated rat hepatocytes

26 November 2018

1 reference

12 December 2020

SIC Task Force appraisal of clinical diagnostic criteria for parkinsonian disorders

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12 December 2020

Biology and pathology of the mitochondrion

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12 December 2020

Regulation of the intracellular distribution of cytoplasmic dynein by serum factors and calcium

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12 December 2020

Hepatic autophagy and intracellular ATP a morphometric study

1 reference

12 December 2020

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

1 reference

12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

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12 December 2020

Identifiers

DOI

10.1093/HMG/DDS309

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22843496

1 reference