Interleukin-1β biosynthesis inhibition reduces acute seizures and drug resistant chronic epileptic activity in mice (Q30500480)

14 October 2017

Interleukin-1β biosynthesis inhibition reduces acute seizures and drug resistant chronic epileptic activity in mice (English)

1 reference

14 October 2017

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1 reference

14 October 2017

Annamaria Vezzani

1 reference

14 October 2017

Mattia Maroso

1 reference

14 October 2017

Silvia Balosso

1 reference

14 October 2017

Teresa Ravizza

1 reference

14 October 2017

Valentina Iori

1 reference

14 October 2017

Christopher Ian Wright

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14 October 2017

1 April 2011

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14 October 2017

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14 October 2017

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14 October 2017

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14 October 2017

304-315

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The role of inflammation in epilepsy

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

ICE/caspase 1 inhibitors and IL-1beta receptor antagonists as potential therapeutics in epilepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

The role of interleukin-1beta in febrile seizures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Communication between neurons and astrocytes: relevance to the modulation of synaptic and network activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Interleukin-1 (IL-1): a central regulator of stress responses.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Antagonism of peripheral inflammation reduces the severity of status epilepticus.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Characteristics and clinical significance of subclinical seizures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

The role of cytokines in the pathophysiology of epilepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Plasma corticosterone, dexamethasone (DEX) suppression and DEX/CRH tests in a rat model of genetic vulnerability to depression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Inflammatory caspases: targets for novel therapies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Status epilepticus induces time-dependent neuronal and astrocytic expression of interleukin-1 receptor type I in the rat limbic system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Interleukin-1beta contributes to the generation of experimental febrile seizures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Overview of benefit/risk of biological agents

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Increased neuronal beta-amyloid precursor protein expression in human temporal lobe epilepsy: association with interleukin-1 alpha immunoreactivity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Cytokines, glucocorticoids and neuroendocrine function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

A mechanism for glucocorticoid toxicity in the hippocampus: increased neuronal vulnerability to metabolic insults.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Regulation of serum tumor necrosis factor in glucocorticoid-sensitive and -resistant rodent endotoxin shock models

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Auras and subclinical seizures: characteristics and prognostic significance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Effects of kainic acid on messenger RNA levels of IL-1 beta, IL-6, TNF alpha and LIF in the rat brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Glucocorticoids exacerbate kainic acid-induced extracellular accumulation of excitatory amino acids in the rat hippocampus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Immunohistochemical localization of interleukin-1beta, interleukin-1 receptor antagonist and interleukin-1beta converting enzyme/caspase-1 in the rat brain after peripheral administration of kainic acid

20 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Inactivation of caspase-1 in rodent brain: a novel anticonvulsive strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

The IL-1beta system in epilepsy-associated malformations of cortical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Botulinum neurotoxin E (BoNT/E) reduces CA1 neuron loss and granule cell dispersion, with no effects on chronic seizures, in a mouse model of temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Glutamate receptor antagonists and benzodiazepine inhibit the progression of granule cell dispersion in a mouse model of mesial temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Antiepileptic effects of botulinum neurotoxin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Long-lasting antiepileptic effects of levetiracetam against epileptic seizures in the spontaneously epileptic rat (SER): differentiation of levetiracetam from conventional antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Pharmacokinetic considerations of dexamethasone-induced developmental toxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Novel glucocorticoid effects on acute inflammation in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0039-Z

Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101825

Cytokine effects on glutamate uptake by human astrocytes

26 November 2018

1 reference

12 December 2020

Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy

1 reference

12 December 2020

Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus

1 reference

12 December 2020

ICE/Caspase-1 inhibitors as novel anti-inflammatory drugs

1 reference

12 December 2020

Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

1 reference

12 December 2020

10.1007/S13311-011-0039-Z

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

21431948

1 reference