Mechanisms of ascorbate-induced cytotoxicity in pancreatic cancer (Q30492805)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068072%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

title

Mechanisms of ascorbate-induced cytotoxicity in pancreatic cancer (English)

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30 August 2019

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30 August 2019

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30 August 2019

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30 August 2019

Juan Du

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30 August 2019

Sean M Martin

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30 August 2019

Mark Levine

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30 August 2019

Brett A Wagner

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30 August 2019

Sih-han Wang

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30 August 2019

Agshin F Taghiyev

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30 August 2019

Changbin Du

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30 August 2019

language of work or name

English

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publication date

12 January 2010

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30 August 2019

published in

Clinical Cancer Research

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30 August 2019

volume

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30 August 2019

issue

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30 August 2019

page(s)

509-520

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Mitochondrial DNA depletion induces radioresistance by suppressing G2 checkpoint activation in human pancreatic cancer cells.

30 August 2019

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Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects

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Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

14 July 2018

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14 July 2018

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In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis

14 July 2018

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14 July 2018

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14 July 2018

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Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

14 July 2018

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Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

14 July 2018

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Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

14 July 2018

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Vitamin C pharmacokinetics: implications for oral and intravenous use.

14 July 2018

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Cancer: the preconditioning factor in pathogenesis; a new etiologic approach.

14 July 2018

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14 July 2018

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Oxidative stress inhibits apoptosis in human lymphoma cells

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress.

14 July 2018

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Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer

26 November 2018

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The in vitro cytotoxicity of ascorbate depends on the culture medium used to perform the assay and involves hydrogen peroxide

26 November 2018

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Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells.

26 November 2018

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Pharmacokinetic model of ascorbic acid in healthy male volunteers during depletion and repletion

26 November 2018

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12 December 2020

Cancer: a collagen disease, secondary to a nutritional deficiency

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12 December 2020

Treatment and survival in 13560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: An epidemiological study

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12 December 2020

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12 December 2020

Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury

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12 December 2020

The orthomolecular treatment of cancer. II. Clinical trial of high-dose ascorbic acid supplements in advanced human cancer

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12 December 2020

10.1158/1078-0432.CCR-09-1713

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068072%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference

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30 August 2019

PubMed publication ID

20068072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068072%20AND%20SRC:MED&resulttype=core&format=json