Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation (Q30489795)

19 August 2017

Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation (English)

1 reference

19 August 2017

1 reference

Craig W Lindsley

1 reference

19 August 2017

Lei Ma

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19 August 2017

Matthew A Seager

1 reference

19 August 2017

Marion Wittmann

1 reference

19 August 2017

Marlene Jacobson

1 reference

19 August 2017

Denise Bickel

1 reference

19 August 2017

Maryann Burno

1 reference

19 August 2017

Keith Jones

1 reference

19 August 2017

Valerie Kuzmick Graufelds

1 reference

19 August 2017

Guangping Xu

1 reference

19 August 2017

Michelle Pearson

1 reference

19 August 2017

Alexander McCampbell

1 reference

19 August 2017

Renee Gaspar

1 reference

19 August 2017

Paul Shughrue

1 reference

19 August 2017

Andrew Danziger

1 reference

19 August 2017

Christopher Regan

1 reference

19 August 2017

Rose Flick

1 reference

19 August 2017

Danette Pascarella

1 reference

19 August 2017

Susan Garson

1 reference

19 August 2017

Scott Doran

1 reference

19 August 2017

Constantine Kreatsoulas

1 reference

19 August 2017

Lone Veng

1 reference

19 August 2017

William Shipe

1 reference

19 August 2017

Scott Kuduk

1 reference

19 August 2017

Cyrille Sur

1 reference

19 August 2017

Gene Kinney

1 reference

19 August 2017

Guy R Seabrook

1 reference

19 August 2017

William J Ray

1 reference

19 August 2017

language of work or name

English

0 references

publication date

26 August 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

1 reference

19 August 2017

106

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19 August 2017

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19 August 2017

15950-15955

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A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

M1 muscarinic receptors inhibit L-type Ca2+ current and M-current by divergent signal transduction cascades

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Allosterism at muscarinic receptors: ligands and mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Activation of the intracerebral cholinergic nerve fibers originating in the basal forebrain increases regional cerebral blood flow in the rat's cortex and hippocampus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

MAPK cascade signalling and synaptic plasticity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Cholinergic modulation of the hippocampus during encoding and retrieval of tone/shock-induced fear conditioning.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Cell-Based High-Throughput Screening Assay System for Monitoring G Protein-Coupled Receptor Activation Using β-Galactosidase Enzyme Complementation Technology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Cellular signaling mechanisms for muscarinic acetylcholine receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Discovery of an ectopic activation site on the M(1) muscarinic receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Crystal structure of rhodopsin: A G protein-coupled receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Acetylcholine in mind: a neurotransmitter correlate of consciousness?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Molecular analysis of the regulation of muscarinic receptor expression and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Abnormalities of neural circuitry in Alzheimer's disease: hippocampus and cortical cholinergic innervation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Acetylcholine as a brain state modulator: triggering and long-term regulation of REM sleep.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Muscarinic acetylcholine receptors: signal transduction through multiple effectors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Microdialysis measurement of cortical and hippocampal acetylcholine release during sleep-wake cycle in freely moving cats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Muscarinic receptor subtypes: Modulation of ion channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Modality-specific retrograde amnesia of fear

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Serum leptin is suppressed by growth hormone therapy in growth hormone-deficient children

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900903106

Scopolamine Impairs Acquisition and Facilitates Consolidation of Fear Conditioning: Differential Effects for Tone vs Context Conditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900903106

Functional acetylcholine muscarinic receptor subtypes in human brain microcirculation: identification and cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900903106

Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900903106

Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine‐induced seizure activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900903106

Sub-chronic administration of zolpidem affects modifications to rat sleep architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0900903106

Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Hyperactivity and intact hippocampus-dependent learning in mice lacking the M1 muscarinic acetylcholine receptor.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2732705

Variation in mRNA expression of alpha-adrenergic, neurokinin and muscarinic receptors amongst four arteries of the rat

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19717450

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0900903106

1 reference

19 August 2017

0 references

1 reference

19 August 2017

PubMed publication ID

19717450

1 reference