A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential (Q30488360)

19 August 2017

A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential (English)

1 reference

molecular dynamics simulation

19 August 2017

0 references

1 reference

19 August 2017

Jonathan R Silva

0 references

David Sept

0 references

Hua Pan

1 reference

19 August 2017

Dick Wu

1 reference

19 August 2017

Ali Nekouzadeh

1 reference

19 August 2017

Keith F Decker

1 reference

19 August 2017

Jianmin Cui

1 reference

19 August 2017

Yoram Rudy

1 reference

19 August 2017

language of work or name

English

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publication date

22 June 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

1 reference

19 August 2017

106

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19 August 2017

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19 August 2017

11102-11106

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Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Closing in on the resting state of the Shaker K(+) channel.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Dynamics of the Kv1.2 voltage-gated K+ channel in a membrane environment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Computational biology in the study of cardiac ion channels and cell electrophysiology.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

How does voltage open an ion channel?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

How far will you go to sense voltage?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Scalable molecular dynamics with NAMD

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

A quantitative assessment of models for voltage-dependent gating of ion channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

A physical model of potassium channel activation: from energy landscape to gating kinetics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Ionic current basis of electrocardiographic waveforms: a model study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Electrostatics of nanosystems: application to microtubules and the ribosome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Gating and flickery block differentially affected by rubidium in homomeric KCNQ1 and heteromeric KCNQ1/KCNE1 potassium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Kramers' diffusion theory applied to gating kinetics of voltage-dependent ion channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Influence of the membrane potential on the free energy of an intrinsic protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Mutations in the hminK gene cause long QT syndrome and suppress lKs function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

VMD: visual molecular dynamics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Comparative protein modelling by satisfaction of spatial restraints

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

A proton pore in a potassium channel voltage sensor reveals a focused electric field

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904505106

An LQT mutant minK alters KvLQT1 trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904505106

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904505106

Focused electric field across the voltage sensor of potassium channels

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700153

Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia

26 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0904505106

Prevalence and prognostic significance of short QT interval in a middle-aged Finnish population

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19549851

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0904505106

1 reference

19 August 2017

0 references

1 reference

19 August 2017

PubMed publication ID

19549851

1 reference