Complement C5 in experimental autoimmune encephalomyelitis (EAE) facilitates remyelination and prevents gliosis (Q30444852)

14 October 2017

Complement C5 in experimental autoimmune encephalomyelitis (EAE) facilitates remyelination and prevents gliosis (English)

1 reference

experimental autoimmune encephalomyelitis

14 October 2017

0 references

Cedric S Raine

1 reference

14 October 2017

Susanna H Weerth

1 reference

14 October 2017

Horea Rus

series ordinal

1 reference

14 October 2017

Moon L Shin

series ordinal

1 reference

14 October 2017

language of work or name

English

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publication date

1 September 2003

1 reference

The American Journal of Pathology

14 October 2017

1 reference

14 October 2017

163

1 reference

14 October 2017

1 reference

14 October 2017

1069-1080

1 reference

The role of the complement cascade in ischemia/reperfusion injury: implications for neuroprotection

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Complement components of the innate immune system in health and disease in the CNS.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Role of porcine P-selectin in complement-dependent adhesion of human leukocytes to porcine endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

The role of complement anaphylatoxin C5a in neurodegeneration: implications in Alzheimer's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Age dependence of clinical and pathological manifestations of autoimmune demyelination. Implications for multiple sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

C1q knock-out mice for the study of complement deficiency in autoimmune disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Intrathecal activation of the complement system and disability in multiple sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Role of complement, chemokines, and regulatory cytokines in acute lung injury

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: the role of the complement system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Sublytic complement attack induces cell cycle in oligodendrocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Activation of the alternative complement pathway and production of factor H by skeletal myotubes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Complement biosynthesis in the central nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

C5a-induced expression of P-selectin in endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Complement activation by isolated myelin: activation of the classical pathway in the absence of myelin-specific antibodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

The fifth component of complement (C5) in the mouse. Analysis of the molecular basis for deficiency

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Release of leukotriene B4 from sublethally injured oligodendrocytes by terminal complement complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Deficiency of the murine fifth complement component (C5). A 2-base pair gene deletion in a 5'-exon

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Antibody-mediated demyelination in experimental allergic encephalomyelitis is independent of complement membrane attack complex formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Complement deficiency and disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Genetic defect in secretion of complement C5 in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Arachidonic acid mobilization and phosphoinositide turnover by the terminal complement complex, C5b-9, in rat oligodendrocyte x C6 glioma cell hybrids.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Effects of membrane attack complex of complement on apoptosis in experimental autoimmune encephalomyelitis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Immunopathology of secondary-progressive multiple sclerosis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

The complement system is an integrated part of the natural innate immune response in the brain

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Complement facilitates early prion pathogenesis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Complement anaphylatoxin C5a neuroprotects through mitogen-activated protein kinase-dependent inhibition of caspase 3.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Complement regulatory molecules on human myelin and glial cells: differential expression affects the deposition of activated complement proteins.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Studies on demyelination in vitro: the requirement of membrane attack components of the complement system.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Myelin vesicles as an in vitro model to study mechanisms of myelin damage by immune effectors

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868269

Terminal complement complexes (SC5b-9) in cerebrospinal fluid in autoimmune nervous system diseases

26 November 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

Intrathecal complement activation in neurological diseases evaluated by analysis of the terminal complement complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

The role of complement in the pathogenesis of experimental allergic encephalomyelitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

Attenuation of experimental autoimmune demyelination in complement-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

Cutting edge: C3, a key component of complement activation, is not required for the development of myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

Kinetics of anaphylatoxin C5a receptor expression during experimental allergic encephalomyelitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

The Membrane Attack Complex of Complement Causes Severe Demyelination Associated with Acute Axonal Injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

Attenuation of experimental allergic encephalomyelitis in complement component 6-deficient rats is associated with reduced complement C9 deposition, P-selectin expression, and cellular infiltrate in spinal cords

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

The complement membrane attack complex stimulates the prostanoid production of cultured glomerular epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

The expression of complement regulatory proteins by adult human oligodendrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963466-9

Antiserum-induced dissociation of myelinogenesis in vitro. An ultrastructural study

7 January 2021

1 reference

12 December 2020

Chronologic neuropathology of relapsing experimental allergic encephalomyelitis in the mouse

1 reference

12 December 2020

Elimination of terminal complement intermediates from the plasma membrane of nucleated cells: the rate of disappearance differs for cells carrying C5b-7 or C5b-8 or a mixture of C5b-8 with a limited number of C5b-9

1 reference

12 December 2020

Recovery of human neutrophils from complement attack: removal of the membrane attack complex by endocytosis and exocytosis

1 reference

12 December 2020

Hydrolysis of myelin basic protein in human myelin by terminal complement complexes

1 reference

12 December 2020

Distinct restriction of complement- and cell-mediated lysis

1 reference

12 December 2020

Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis

1 reference

12 December 2020

Human oligodendrocytes are not sensitive to complement. A study of CD59 expression in the human central nervous system

1 reference

12 December 2020

Complement regulators and receptors in tissues

1 reference

12 December 2020

Inhibition of oligodendrocyte apoptosis by sublytic C5b-9 is associated with enhanced synthesis of bcl-2 and mediated by inhibition of caspase-3 activation

1 reference

12 December 2020

10.1016/S0002-9440(10)63466-9

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

12937147

1 reference