JNK-mediated phosphorylation of Cdc25C regulates cell cycle entry and G(2)/M DNA damage checkpoint. (Q30432395)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20220133%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

JNK-mediated phosphorylation of Cdc25C regulates cell cycle entry and G(2)/M DNA damage checkpoint (English)

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19 January 2020

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19 January 2020

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19 January 2020

Toshiya Tsuji

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19 January 2020

Janet V Cross

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19 January 2020

Roger J Davis

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19 January 2020

Dennis J Templeton

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19 January 2020

Wei Jiang

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19 January 2020

language of work or name

English

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publication date

10 March 2010

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Journal of Biological Chemistry

19 January 2020

published in

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19 January 2020

volume

285

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19 January 2020

issue

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19 January 2020

page(s)

14217-14228

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JNK inhibitor SP600125 promotes the formation of polymerized tubulin, leading to G2/M phase arrest, endoreduplication, and delayed apoptosis

19 January 2020

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Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.

20 June 2018

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Up-regulation of SEPT9_v1 stabilizes c-Jun-N-terminal kinase and contributes to its pro-proliferative activity in mammary epithelial cells.

20 June 2018

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JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis.

20 June 2018

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The c-Jun N-terminal kinase JNK functions upstream of Aurora B to promote entry into mitosis

20 June 2018

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Basal c-Jun N-terminal kinases promote mitotic progression through histone H3 phosphorylation

20 June 2018

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Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis

20 June 2018

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Autophosphorylation properties of inactive and active JNK2.

20 June 2018

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CDC25 phosphatases in cancer cells: key players? Good targets?

20 June 2018

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A functional role for p38 MAPK in modulating mitotic transit in the absence of stress

20 June 2018

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Rewired ERK-JNK signaling pathways in melanoma

20 June 2018

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Cdc25 and Wee1: analogous opposites?

20 June 2018

1 reference

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Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition

20 June 2018

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c-Jun NH(2)-terminal kinase 2alpha2 promotes the tumorigenicity of human glioblastoma cells

20 June 2018

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The anaphase promoting complex/cyclosome: a machine designed to destroy

20 June 2018

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H2AX is a target of the JNK signaling pathway that is required for apoptotic DNA fragmentation

20 June 2018

1 reference

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Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

20 June 2018

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Ubiquitin and SUMO systems in the regulation of mitotic checkpoints

20 June 2018

1 reference

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The when and wheres of CDC25 phosphatases

20 June 2018

1 reference

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Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers

20 June 2018

1 reference

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Mitogen-activated protein kinases in cell-cycle control

20 June 2018

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Mammalian cyclin-dependent kinases

20 June 2018

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From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance

20 June 2018

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MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation

20 June 2018

1 reference

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Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation

20 June 2018

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Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells

20 June 2018

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Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

20 June 2018

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C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma.

20 June 2018

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Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors

20 June 2018

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Elevated JNK activation contributes to the pathogenesis of human brain tumors

20 June 2018

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Targets of c-Jun NH(2)-terminal kinase 2-mediated tumor growth regulation revealed by serial analysis of gene expression

20 June 2018

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Biological methods for cell-cycle synchronization of mammalian cells

20 June 2018

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Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

20 June 2018

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c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells.

20 June 2018

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

20 June 2018

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Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner

20 June 2018

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Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

20 June 2018

1 reference

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Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

20 June 2018

1 reference

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Involvement of c-jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by cardiotoxin III (Naja naja atra) in K562 leukemia cells.

20 June 2018

1 reference

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SAPK/JNK regulates cdc2/cyclin B kinase through phosphorylation and inhibition of cdc25c

21 January 2018

1 reference

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Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation.

21 January 2018

1 reference

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Stress-activated mitogen-activated protein kinases c-Jun NH2-terminal kinase and p38 target Cdc25B for degradation.

21 January 2018

1 reference

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Inhibition of JNK2 disrupts anaphase and produces aneuploidy in mammalian cells.

21 January 2018

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Chemical genetic analysis of the time course of signal transduction by JNK

21 January 2018

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PubMed

12 December 2020

JNK2 is a positive regulator of the cJun transcription factor

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PubMed

12 December 2020

The JNK signal transduction pathway

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PubMed

12 December 2020

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.121848

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20220133%20AND%20SRC:MED&resulttype=core&format=json

release_zlpsowpdgbbnbnqov6fhpyszga

19 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/zlpsowpdgbbnbnqov6fhpyszga

24 November 2022

mapped directly with Wikidata item

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19 January 2020

PubMed publication ID

20220133

1 reference

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