Atomic level architecture of group I introns revealed (Q30438980)

21 June 2017

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title

Atomic level architecture of group I introns revealed (English)

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21 June 2017

Thomas R Cech

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21 June 2017

Quentin Vicens

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language of work or name

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13 December 2005

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Trends in Biochemical Sciences

21 June 2017

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inferred from page(s)

published in

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21 June 2017

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21 June 2017

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21 June 2017

page(s)

41-51

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VMD: visual molecular dynamics

21 June 2017

cites work

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11 October 2022

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Gene discovery by ribozyme and siRNA libraries

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Excised group II introns in yeast mitochondria are lariats and can be formed by self-splicing in vitro

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Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity

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A Group I intron in the nuclear small subunit rRNA gene of Cryptendoxyla hypophloia, an ascomycetous fungus: evidence for a new major class of Group I introns

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Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

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P5abc of the Tetrahymena ribozyme consists of three functionally independent elements

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11 October 2022

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A preorganized active site in the crystal structure of the Tetrahymena ribozyme

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Protein-dependent transition states for ribonucleoprotein assembly

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Minimal catalytic domain of a group I self-splicing intron RNA

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RNA-catalysed carbon–carbon bond formation

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Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing

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Kinetic intermediates in RNA folding

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Isolation of new ribozymes from a large pool of random sequences [see comment]

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Modular engineering of a Group I intron ribozyme

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Basis for structural diversity in homologous RNAs

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ARTS: alignment of RNA tertiary structures

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Origin of life: The RNA world

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Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns

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Probing the role of metal ions in RNA catalysis: kinetic and thermodynamic characterization of a metal ion interaction with the 2'-moiety of the guanosine nucleophile in the Tetrahymena group I ribozyme

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11 October 2022

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Structure of a folding intermediate reveals the interplay between core and peripheral elements in RNA folding

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11 October 2022

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Structural evidence for a two-metal-ion mechanism of group I intron splicing

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11 October 2022

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5' transcript replacement in vitro catalyzed by a group I intron-derived ribozyme

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11 October 2022

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Identifiers

DOI

10.1016/J.TIBS.2005.11.008

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21 June 2017

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