Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells (Q30435476)

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English	Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

16 October 2017

Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells (English)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

1 reference

based on heuristic

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author name string

Samson Amos

1

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Patrick M Martin

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Gregory A Polar

3

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Sarah J Parsons

4

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Europe PubMed Central

PMC publication ID

16 October 2017

Isa M Hussaini

5

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Europe PubMed Central

PMC publication ID

16 October 2017

language of work or name

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publication date

23 December 2004

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Europe PubMed Central

PMC publication ID

16 October 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

16 October 2017

280

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Europe PubMed Central

PMC publication ID

16 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

7729-7738

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway

1 reference

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Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src

1 reference

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Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes

1 reference

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Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

1 reference

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Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation

1 reference

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The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

1 reference

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Biology and treatment of malignant glioma

1 reference

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Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cells

1 reference

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New insights into the regulation of protein kinase C and novel phorbol ester receptors

1 reference

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Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways

1 reference

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Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ce

1 reference

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Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase

1 reference

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Molecular pathogenesis of malignant gliomas

1 reference

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c-Src, receptor tyrosine kinases, and human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Epidermal growth factor receptors: critical mediators of multiple receptor pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

20 June 2018

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

20 June 2018

Protein kinase C delta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

20 June 2018

Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation

1 reference

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Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta

1 reference

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20 June 2018

Specificity within the EGF family/ErbB receptor family signaling network

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20 June 2018

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

20 June 2018

The role of protein kinase C (PKC) in the evolution and proliferation of malignant gliomas, and the application of PKC inhibition as a novel approach to anti-glioma therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Signal characteristics of G protein-transactivated EGF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Induction of senescence in human malignant glioma cells by p16INK4A.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

20 June 2018

Ligands for ErbB-family receptors encoded by a neuregulin-like gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Association between v-Src and protein kinase C delta in v-Src-transformed fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Signal transduction for proliferation of glioma cells in vitro occurs predominantly through a protein kinase C-mediated pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Protein kinase C isozymes and substrates

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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Regulation, substrates and functions of src

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Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1351089

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The potential of protein kinase C as a target for anticancer treatment

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

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Receptor protein-tyrosine kinases and their signal transduction pathways

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Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells

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Protein kinase C and lipid signaling for sustained cellular responses

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Genetic alterations associated with the evolution and progression of astrocytic brain tumours

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Protein kinase C: structure, function, and regulation

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Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

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Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol

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Phorbol diester receptor copurifies with protein kinase C

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The role of protein kinase C in cell surface signal transduction and tumour promotion

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20 June 2018

Autophosphorylation sites on the epidermal growth factor receptor.

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20 June 2018

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

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Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

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Signal transduction by receptors with tyrosine kinase activity

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Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo.

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A negative feedback loop attenuates EGF-induced morphological changes

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Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro

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Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C

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Expression pattern of alpha-protein kinase C in human astrocytomas indicates a role in malignant progression

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Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q

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26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15618223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15618223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/15618223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/15618223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/15618223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling through protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/15618223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15618223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M409056200

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

release_n6hufrq7sjbp3okyyfbhbocbcy

1 reference

https://api.fatcat.wiki/v0/release/n6hufrq7sjbp3okyyfbhbocbcy

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

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