IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection (Q30361079)

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13 March 2020

title

IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection (English)

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13 March 2020

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13 March 2020

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13 March 2020

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13 March 2020

Leo L M Poon

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13 March 2020

Olive T W Li

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13 March 2020

Liyanage P Perera

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13 March 2020

Thomas A Waldmann

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13 March 2020

Polly W Y Mak

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13 March 2020

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Chris K P Mok

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13 March 2020

John M Nicholls

series ordinal

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13 March 2020

language of work or name

English

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publication date

31 March 2014

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Proceedings of the National Academy of Sciences of the United States of America

13 March 2020

published in

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13 March 2020

volume

111

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issue

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page(s)

5676-5681

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Pathogenicity of the novel A/H7N9 influenza virus in mice.

13 March 2020

cites work

1 reference

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Cooperativity between CD8+ T cells, non-neutralizing antibodies, and alveolar macrophages is important for heterosubtypic influenza virus immunity

3 June 2018

1 reference

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Cross-protective immunity against multiple influenza virus subtypes by a novel modified vaccinia Ankara (MVA) vectored vaccine in mice

3 June 2018

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Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies

3 June 2018

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Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms

3 June 2018

1 reference

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Preliminary assessment of the efficacy of a T-cell-based influenza vaccine, MVA-NP+M1, in humans

3 June 2018

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Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

3 June 2018

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Seasonal H1N1 influenza virus infection induces cross-protective pandemic H1N1 virus immunity through a CD8-independent, B cell-dependent mechanism

3 June 2018

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Contributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virus

3 June 2018

1 reference

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Vectors Based on Modified Vaccinia Ankara Expressing Influenza H5N1 Hemagglutinin Induce Substantial Cross-Clade Protective Immunity

3 June 2018

1 reference

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Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1.

3 June 2018

1 reference

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T cell-mediated protection against lethal 2009 pandemic H1N1 influenza virus infection in a mouse model

3 June 2018

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Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys

3 June 2018

1 reference

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Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

3 June 2018

1 reference

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Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population

3 June 2018

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Candidate influenza vaccines based on recombinant modified vaccinia virus Ankara.

3 June 2018

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Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice

3 June 2018

1 reference

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Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals

3 June 2018

1 reference

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Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

3 June 2018

1 reference

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

3 June 2018

1 reference

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Alternative activation of macrophages

3 June 2018

1 reference

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Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses.

3 June 2018

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CD4 T cell-mediated protection from lethal influenza: perforin and antibody-mediated mechanisms give a one-two punch

3 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24706798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1403684111

1 reference

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13 March 2020

0 references

1 reference

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13 March 2020

PubMed publication ID

24706798

1 reference

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