The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. (Q30332511)

14 September 2017

The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. (English)

1 reference

14 September 2017

1 reference

Arend Sidow

1 reference

14 September 2017

Dennis C Ko

1 reference

14 September 2017

Jonathan Binkley

series ordinal

1 reference

14 September 2017

Matthew P Scott

series ordinal

1 reference

14 September 2017

language of work or name

English

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publication date

18 February 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 September 2017

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inferred from page(s)

published in

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14 September 2017

100

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14 September 2017

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14 September 2017

2518-2525

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Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Inference of functional regions in proteins by quantification of evolutionary constraints

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Niemann-Pick disease type C: spectrum of HE1 mutations and genotype/phenotype correlations in the NPC2 group

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Identification of HE1 as the second gene of Niemann-Pick C disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Transmembrane molecular pump activity of Niemann-Pick C1 protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Crystal structure of human GM2-activator protein with a novel beta-cup topology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Signaling and subcellular targeting by membrane-binding domains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Enhanced genome annotation using structural profiles in the program 3D-PSSM

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

The fatty acid transport function of fatty acid-binding proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Structure and lipid transport mechanism of a StAR-related domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

CAFASP-1: critical assessment of fully automated structure prediction methods

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Tertiary structure of the major house dust mite allergen Der p 2: sequential and structural homologies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Plasma membranes contain half the phospholipid and 90% of the cholesterol and sphingomyelin in cultured human fibroblasts.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

Cloning and analysis of mRNAs expressed specifically in the human epididymis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151373

A structural EM algorithm for phylogenetic inference.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0530027100

The GM2 activator protein, its roles as a co-factor in GM2 hydrolysis and as a general glycolipid transport protein.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0530027100

Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12591949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12591949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Circulation of cholesterol between lysosomes and the plasma membrane

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12591949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0530027100

1 reference

14 September 2017

0 references

1 reference

14 September 2017

PubMed publication ID

12591949

1 reference