The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor (Q30195438)

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scientific article published on April 1, 1992

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English	The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor	scientific article published on April 1, 1992

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

phosphorylation

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3

object named as

Fantl WJ

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Lewis T. Williams

4

object named as

Williams LT

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jaime A. Escobedo

2

object named as

Escobedo JA

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

author name string

A. Klippel

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1312663

12 September 2022

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publication date

1 April 1992

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Europe PubMed Central

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17 August 2017

full work available at URL

http://mcb.asm.org/cgi/content/abstract/12/4/1451

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1312663

12 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1312663/?tool=EBI

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1312663

12 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1312663/pdf/?tool=EBI

Portable Document Format

online access status

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1312663

12 September 2022

https://europepmc.org/articles/PMC369586

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1312663

12 September 2022

https://europepmc.org/articles/PMC369586?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1312663

12 September 2022

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

17 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

1451-1459

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1 reference

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SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat

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Platelet-derived growth factor receptors expressed by cDNA transfection couple to a diverse group of cellular responses associated with cell proliferation

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Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

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PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1 reference

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

1 reference

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3 June 2018

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

1 reference

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3 June 2018

Src homology region 2 domains direct protein-protein interactions in signal transduction

1 reference

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3 June 2018

Use of T7 RNA polymerase to direct expression of cloned genes

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3 June 2018

Purification and characterization of phosphoinositide 3-kinase from rat liver

1 reference

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3 June 2018

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369586

3 June 2018

Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369586

3 June 2018

Purification and characterization of bovine brain type I phosphatidylinositol kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369586

3 June 2018

PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369586

3 June 2018

Two types of phosphatidylinositol 3-kinase from bovine thymus. Monomer and heterodimer form

1 reference

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3 June 2018

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369586

3 June 2018

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=369586

3 June 2018

The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110

1 reference

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3 June 2018

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

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3 June 2018

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1 reference

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3 June 2018

Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins

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A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

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The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity

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Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity

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Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

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A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.

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An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinase

1 reference

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12 December 2020

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Identifiers

10.1128/MCB.12.4.1451

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

10.1128/MCB.12.4.1451-1459.1992

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1312663

12 September 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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