Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase. (Q30157084)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840380%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase (English)

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10 February 2020

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10 February 2020

Francesca Di Nunzio

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10 February 2020

Alan Engelman

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10 February 2020

Mohd J Dar

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10 February 2020

Lavanya Krishnan

series ordinal

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10 February 2020

Ming-Chieh Shun

series ordinal

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10 February 2020

Dag E Helland

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10 February 2020

publication date

19 October 2009

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10 February 2020

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10 February 2020

volume

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10 February 2020

page(s)

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describes a project that uses

10 February 2020

ImageQuant

object named as

Image Quant

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro

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Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin protein

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Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication

3 June 2018

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Genetic analyses of conserved residues in the carboxyl-terminal domain of human immunodeficiency virus type 1 integrase

3 June 2018

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Recombinant human immunodeficiency virus type 1 integrase exhibits a capacity for full-site integration in vitro that is comparable to that of purified preintegration complexes from virus-infected cells

3 June 2018

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Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication

3 June 2018

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Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins

3 June 2018

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Requirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase.

3 June 2018

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The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

3 June 2018

1 reference

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Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus

3 June 2018

1 reference

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Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

3 June 2018

1 reference

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Role of the nonspecific DNA-binding region and alpha helices within the core domain of retroviral integrase in selecting target DNA sites for integration

3 June 2018

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Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selection

3 June 2018

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Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes

3 June 2018

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A quantitative assay for HIV DNA integration in vivo

3 June 2018

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Repair of gaps in retroviral DNA integration intermediates

3 June 2018

1 reference

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Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

3 June 2018

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Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

3 June 2018

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X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

3 June 2018

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3 June 2018

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3 June 2018

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Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex.

3 June 2018

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Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

3 June 2018

1 reference

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Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

3 June 2018

1 reference

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The Core Domain of HIV-1 Integrase Recognizes Key Features of Its DNA Substrates

3 June 2018

1 reference

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Heterogeneity in recombinant HIV-1 integrase corrected by site-directed mutagenesis: the identification and elimination of a protease cleavage site

3 June 2018

1 reference

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Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Monoclonal antibodies against human immunodeficiency virus type 1 integrase: epitope mapping and differential effects on integrase activities in vitro

3 June 2018

1 reference

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Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Solution structure of the DNA binding domain of HIV-1 integrase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Catalytic domain of human immunodeficiency virus type 1 integrase: identification of a soluble mutant by systematic replacement of hydrophobic residues

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Two bases are deleted from the termini of HIV-1 linear DNA during integrative recombination

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNa termini mediated by the viral integrase protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Mutational analysis of the integrase protein of human immunodeficiency virus type 2

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Quantitative analysis of HIV-1 preintegration complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S).

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Modeling HIV-1 integrase complexes based on their hydrodynamic properties

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Mapping Features of HIV-1 Integrase Near Selected Sites on Viral and Target DNA Molecules in an Active Enzyme−DNA Complex by Photo-Cross-Linking

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770994

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

26 November 2018

1 reference

12 December 2020

Biophysical and enzymatic properties of the catalytic domain of HIV-1 integrase.

1 reference

12 December 2020

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

12 December 2020

Modeling the late steps in HIV-1 retroviral integrase-catalyzed DNA integration

1 reference

12 December 2020

Identifiers

DOI

10.1186/1742-4690-6-94

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840380%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840380%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

19840380

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840380%20AND%20SRC:MED&resulttype=core&format=json