Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines (Q39945200)

15 September 2017

Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines (English)

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15 September 2017

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Nikhil M Vad

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15 September 2017

Garret Yount

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15 September 2017

Dan Moore

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15 September 2017

Jon Weidanz

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15 September 2017

Majid Y Moridani

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15 September 2017

language of work or name

English

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publication date

1 April 2009

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Journal of Pharmaceutical Sciences

15 September 2017

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15 September 2017

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15 September 2017

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15 September 2017

1409-1425

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Metabolic bioactivation and toxicity of ethyl 4-hydroxybenzoate in human SK-MEL-28 melanoma cells.

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Rapid determination of reduced and oxidized glutathione levels using a new thiol-masking reagent and the enzymatic recycling method: application to the rat liver and bile samples

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Biochemical basis of 4-hydroxyanisole induced cell toxicity towards B16-F0 melanoma cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Structural toxicity relationship of 4-alkoxyphenols' cytotoxicity towards murine B16-F0 melanoma cell line

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

22 September 2017

Tissue sulfhydryl groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Oxidative damage to DNA: relation to species metabolic rate and life span

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

A note on the inhibition of DT-diaphorase by dicoumarol

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Hydroxyanisole depigmentation: In-vitro studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Tyrosinase activity in a highly pigmented human melanoma and in negro skin.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Studies on the mechanism of action of quinone antitumor agents

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Structure-activity relationships defining the cytotoxicity of catechol analogues against human malignant melanoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

1-bromoalkanes as new potent nontoxic glutathione depletors in isolated rat hepatocytes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Relationship between melanogenesis, glutathione levels and melphalan toxicity in human melanoma cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Cytotoxicity of a selected series of substituted phenols towards cultured melanoma cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Application of quantitative structure-toxicity relationships for the comparison of the cytotoxicity of 14 p-benzoquinone congeners in primary cultured rat hepatocytes versus PC12 cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Catalytic oxidation of acetaminophen by tyrosinase in the presence of L-proline: a kinetic study.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Quantification of acetaminophen by oxidation with tyrosinase in the presence of Besthorn's hydrazone

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Tyrosinase-mediated oxidation of acetaminophen to 4-acetamido-o-benzoquinone.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Metabolic activation of 3-hydroxyanisole by isolated rat hepatocytes

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Metabolic activation of 4-hydroxyanisole by isolated rat hepatocytes

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Glutathione protects metastatic melanoma cells against oxidative stress in the murine hepatic microvasculature.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Melanogenesis-targeted anti-melanoma pro-drug development: effect of side-chain variations on the cytotoxicity of tyrosinase-generated ortho-quinones in a model screening system

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Major primary cytotoxic product of 4-hydroxyanisole oxidation by mushroom tyrosinase is 4-methoxy ortho benzoquinone

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650003

Initial mushroom tyrosinase-catalysed oxidation product of 4-hydroxyanisole is 4-methoxy-ortho-benzoquinone

20 August 2018

1 reference

12 December 2020

Isolation of microsomal subfractions by use of density gradients

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12 December 2020

5,6-Dihydroxyindole is a melanin precursor showing potent cytotoxicity

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12 December 2020

Effect of acetaminophen (paracetamol) and its antagonists on glutathione (GSH) content in rat liver

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12 December 2020

Increased microsomal oxidation of alcohols after pyrazole treatment and its similarities to the induction by ethanol consumption

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12 December 2020

Role of glutathione depletion in the cytotoxicity of acetaminophen in a primary culture system of rat hepatocytes

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12 December 2020

Mechanism of antitumoral activity of catechols in culture

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12 December 2020

Cyclosporin A-sensitive and insensitive mechanisms produce the permeability transition in mitochondria

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12 December 2020

Studies on the reactions between human tyrosinase, superoxide anion, hydrogen peroxide and thiols

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12 December 2020

In vitro assessment of the structure – activity relationship of tyrosinase-dependent cytotoxicity of a series of substituted phenols

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12 December 2020

Phase I study of intravenous 4-hydroxyanisole

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12 December 2020

The Bradford method for protein quantitation

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12 December 2020

Interaction of Nitric Oxide with 2-Thio-5-nitrobenzoic Acid: Implications for the Determination of Free Sulfhydryl Groups by Ellman's Reagent

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12 December 2020

Identifiers

DOI

10.1002/JPS.21505

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15 September 2017

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15 September 2017

PubMed publication ID

18759348

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