ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry (Q39923417)

15 September 2017

title

ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry (English)

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15 September 2017

main subject

hepatocellular carcinoma

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Toshikazu Yoshikawa

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15 September 2017

Masafumi Taniwaki

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15 September 2017

Keika Zen

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15 September 2017

Kohichiroh Yasui

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15 September 2017

Tomoaki Nakajima

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15 September 2017

Yoh Zen

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15 September 2017

Kan Zen

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15 September 2017

Yasuyuki Gen

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15 September 2017

Hironori Mitsuyoshi

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15 September 2017

Masahito Minami

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15 September 2017

Shoji Mitsufuji

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15 September 2017

Shinji Tanaka

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15 September 2017

Yoshito Itoh

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15 September 2017

Yasuni Nakanuma

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15 September 2017

Shigeki Arii

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15 September 2017

Takeshi Okanoue

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15 September 2017

language of work or name

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1 February 2009

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Genes, Chromosomes and Cancer

15 September 2017

published in

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15 September 2017

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15 September 2017

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15 September 2017

page(s)

109-120

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ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo.

15 September 2017

cites work

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A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

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Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

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High-resolution analysis of DNA copy number using oligonucleotide microarrays

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Abl-kinase-sensitive levels of ERK5 and its intrinsic basal activity contribute to leukaemia cell survival

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Multifunctional role of Erk5 in multiple myeloma

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Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

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Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma

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7 January 2021

Regulation of the G2-M cell cycle progression by the ERK5-NFkappaB signaling pathway

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7 January 2021

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

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7 January 2021

Dynamic model based algorithms for screening and genotyping over 100 K SNPs on oligonucleotide microarrays

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7 January 2021

Hepatocellular carcinoma: an epidemiologic view

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7 January 2021

Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control

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7 January 2021

Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2

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7 January 2021

Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas

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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

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7 January 2021

Erk5 is activated and acts as a survival factor in mitosis.

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7 January 2021

Role of the BMK1/ERK5 signaling pathway: lessons from knockout mice

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7 January 2021

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

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7 January 2021

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

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7 January 2021

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

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7 January 2021

Large-scale genotyping of complex DNA.

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7 January 2021

Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen

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7 January 2021

IGF-II induces CREB phosphorylation and cell survival in human lung cancer cells

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7 January 2021

Amplification and expression of the c-myc oncogene in human lung cancer cell lines

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7 January 2021

Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays.

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7 January 2021

Parallel genotyping of over 10,000 SNPs using a one-primer assay on a high-density oligonucleotide array

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7 January 2021

Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer

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7 January 2021

MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion

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7 January 2021

Genome-wide detection of allelic imbalance using human SNPs and high-density DNA arrays

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7 January 2021

Expression of tissue factor mRNA and invasion of blood vessels by tumor cells in non-small cell lung cancer

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7 January 2021

Activation of cyclin D1 expression by the ERK5 cascade

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7 January 2021

A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays

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7 January 2021

MAPK signalling: ERK5 versus ERK1/2.

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7 January 2021

PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas

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7 January 2021

Characterization of cell lines established from human hepatocellular carcinoma

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7 January 2021

The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module

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7 January 2021

MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src

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7 January 2021

Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma

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7 January 2021

Regulation of cellular functions by the ERK5 signalling pathway

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7 January 2021

Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray

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7 January 2021

Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA.

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7 January 2021

TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas

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7 January 2021

Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma

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7 January 2021

Activation of ErbB2 by overexpression or by transmembrane neuregulin results in differential signaling and sensitivity to herceptin

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7 January 2021

An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays

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7 January 2021

Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis

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7 January 2021

Identifiers

DOI

10.1002/GCC.20624

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15 September 2017

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