Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. (Q39909317)

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English	Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.	scientific article

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15 September 2017

title

Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. (English)

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5065715

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15 September 2017

main subject

Cas9

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author

Martin Jínek

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3

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5065715

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15 September 2017

author name string

Carolin Anders

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1

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5065715

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15 September 2017

Katja Bargsten

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2

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5065715

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15 September 2017

publication date

1 March 2016

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5065715

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15 September 2017

published in

Molecular Cell

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5065715

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15 September 2017

volume

61

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Europe PubMed Central

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5065715

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15 September 2017

issue

6

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5065715

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page(s)

895-902

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5065715

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cites work

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Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome

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22 September 2017

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Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

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22 September 2017

Conformational control of DNA target cleavage by CRISPR-Cas9.

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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

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22 September 2017

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

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Engineered CRISPR-Cas9 nucleases with altered PAM specificities

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22 September 2017

In vivo genome editing using Staphylococcus aureus Cas9

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22 September 2017

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

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22 September 2017

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

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22 September 2017

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

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22 September 2017

Development and applications of CRISPR-Cas9 for genome engineering

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22 September 2017

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

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22 September 2017

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

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22 September 2017

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

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22 September 2017

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

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22 September 2017

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

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22 September 2017

CRISPR-mediated adaptive immune systems in bacteria and archaea

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22 September 2017

RNA-programmed genome editing in human cells

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22 September 2017

RNA-guided human genome engineering via Cas9

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22 September 2017

Multiplex genome engineering using CRISPR/Cas systems

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22 September 2017

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

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22 September 2017

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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22 September 2017

Towards automated crystallographic structure refinement with phenix.refine

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22 September 2017

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22 September 2017

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22 September 2017

In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide RNA and a DNA Target

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Targeted gene editing by transfection of in vitro reconstituted Streptococcus thermophilus Cas9 nuclease complex

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crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus

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3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures

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Identifiers

DOI

10.1016/J.MOLCEL.2016.02.020

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Europe PubMed Central

PMC publication ID

5065715

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15 September 2017

PMC publication ID

5065715

1 reference

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Europe PubMed Central

PMC publication ID

5065715

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15 September 2017

PubMed publication ID

26990992

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Europe PubMed Central

PMC publication ID

5065715

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15 September 2017

 

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