Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. (Q39867000)

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scientific article published on 27 March 2009

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English	Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.	scientific article published on 27 March 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

15 September 2017

Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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based on heuristic

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based on heuristic

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based on heuristic

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Manon van Engeland

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object named as

Manon van Engeland

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15 September 2017

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object named as

Gerrit A Meijer

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15 September 2017

author name string

Sarah Derks

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Linda J W Bosch

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Hanneke E C Niessen

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Peter T M Moerkerk

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Sandra M van den Bosch

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Beatriz Carvalho

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Sandra Mongera

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J Willem Voncken

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Adriaan P de Bruïne

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15 September 2017

James G Herman

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15 September 2017

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publication date

27 March 2009

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15 September 2017

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15 September 2017

30

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15 September 2017

1041-1048

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15 September 2017

Genetic alterations during colorectal-tumor development

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Identification of a chromosome 18q gene that is altered in colorectal cancers

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

The DCC gene: structural analysis and mutations in colorectal carcinomas

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Gene silencing in cancer in association with promoter hypermethylation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

The epigenomics of cancer

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Role of the dependence receptor DCC in colorectal cancer pathogenesis

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Chromosomal instability in flat adenomas and carcinomas of the colon.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Angiogenesis gene expression profiling in xenograft models to study cellular interactions

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Human colon cancer cells deficient in DCC produce abnormal transcripts in progression of carcinogenesis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

CpG islands in vertebrate genomes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

DCC promoter hypermethylation in esophageal squamous cell carcinoma.

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Oesophageal squamous cell carcinoma may develop within a background of accumulating DNA methylation in normal and dysplastic mucosa

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

DNA methylation patterns and epigenetic memory

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Control of developmental regulators by Polycomb in human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP073

21 January 2018

Identifiers

10.1093/CARCIN/BGP073

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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